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Table 2 The assessment of the risk of bias in each cohort study using the Newcastle-Ottawa scale

From: Relationship between circulating tumor cells and tumor response in colorectal cancer patients treated with chemotherapy: a meta-analysis

Study

Selection (0–4)

Comparability (0–2)

Outcome (0–3)

Total

REC

SNEC

AE

DO

SC

AF

AO

FU

AFU

Barbazan 2014 [30]

0

1

1

1

0

0

1

1

0

5

Kuboki 2013 [34]

0

1

1

1

0

0

1

0

0

4

Lu 2013 [36]

1

1

1

1

0

0

1

1

1

7

Iinuma 2013 [35]

1

1

1

1

0

0

1

1

0

6

Sastre 2012 [26]

1

1

1

1

0

0

1

1

0

6

de Albuquerque 2012 [27]

0

1

1

1

0

0

1

0

1

5

Matsusaka 2011 [28]

0

1

1

1

1

0

1

1

0

6

Konigsberg 2010 [33]

0

1

1

1

0

0

1

0

0

4

Yalcin 2010 [32]

0

1

1

1

0

0

1

0

0

4

Tol 2010 [29]

1

1

1

1

0

0

1

1

0

6

Yen 2009 [37]

1

1

1

1

0

0

1

1

0

6

Cohen2008 [11]

0

1

1

1

0

0

1

1

0

5

Staritz 2004 [31]

0

1

1

1

0

0

1

0

1

5

  1. NOTE. REC: representativeness of the exposed cohort; SNEC: selection of the non-exposed cohort; AE: ascertainment of exposure; DO: demonstration that outcome of interest was not present at start of study; SC: study controls for age, sex; AF: study controls for any additional factors (chemoradiotherapy, curative resection); AO: assessment of outcome; FU: follow-up long enough (36 Months) for outcomes to occur; AFU: adequacy of follow-up of cohorts (≥90%). ‘1’ means that the study is satisfied the item, and ‘0’ means the opposite situation.