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Table 2 The assessment of the risk of bias in each cohort study using the Newcastle-Ottawa scale

From: Relationship between circulating tumor cells and tumor response in colorectal cancer patients treated with chemotherapy: a meta-analysis

Study Selection (0–4) Comparability (0–2) Outcome (0–3) Total
REC SNEC AE DO SC AF AO FU AFU
Barbazan 2014 [30] 0 1 1 1 0 0 1 1 0 5
Kuboki 2013 [34] 0 1 1 1 0 0 1 0 0 4
Lu 2013 [36] 1 1 1 1 0 0 1 1 1 7
Iinuma 2013 [35] 1 1 1 1 0 0 1 1 0 6
Sastre 2012 [26] 1 1 1 1 0 0 1 1 0 6
de Albuquerque 2012 [27] 0 1 1 1 0 0 1 0 1 5
Matsusaka 2011 [28] 0 1 1 1 1 0 1 1 0 6
Konigsberg 2010 [33] 0 1 1 1 0 0 1 0 0 4
Yalcin 2010 [32] 0 1 1 1 0 0 1 0 0 4
Tol 2010 [29] 1 1 1 1 0 0 1 1 0 6
Yen 2009 [37] 1 1 1 1 0 0 1 1 0 6
Cohen2008 [11] 0 1 1 1 0 0 1 1 0 5
Staritz 2004 [31] 0 1 1 1 0 0 1 0 1 5
  1. NOTE. REC: representativeness of the exposed cohort; SNEC: selection of the non-exposed cohort; AE: ascertainment of exposure; DO: demonstration that outcome of interest was not present at start of study; SC: study controls for age, sex; AF: study controls for any additional factors (chemoradiotherapy, curative resection); AO: assessment of outcome; FU: follow-up long enough (36 Months) for outcomes to occur; AFU: adequacy of follow-up of cohorts (≥90%). ‘1’ means that the study is satisfied the item, and ‘0’ means the opposite situation.