Figure 5

DEK expression is related to irinotecan response and correlates with poor outcome in KRAS wt patients. A) Representative IHC images for low, medium or high staining intensities of DEK expression levels. B) Kaplan-Meier plot shows a significant association between high DEK level and lower progression-free survival after irinotecan-based treatment in KRAS wt patients (P = 0.010).