RNA profile of liver perfusate exosomes. (A) A representative Bioanalyzer electropherogram of liver perfusate exosomes, showing a classical exosomal RNA profile, lacking the ribosomal 18S and 28S subunits, and enriched in lower molecular weight RNAs. (B) Cluster analysis of the miRNAs found in exosomes from patients and cell lines, showing a clear similarity between the patients. (C) A close-up of a specific portion of the cluster analysis, highlighting three miRNA clusters. Cluster 3 shows miRNAs that are more associated with patients than control cell lines. Abbreviations: P1-9 = Patient 1 to 9, C1-3 = Cluster 1 to 3, NI = Not identified.