Analysis of the secreted forms of ANXA1 and of their effects on PC cell motility. A, LC-HRMS/MS spectrum, peaks refer to all the discovered peptide fragments. The data are representative of 5 experiments with similar results. B, Effects of MIA PaCa-2 supernatants on PANC-1 cells and viceversa in a wound-healing assay. Statistical significance was calculated using unpaired t-test between control and treated cells, ***p < 0.001. Data are means ± SEM (n = 5).