Figure 5From: Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-κB pathway Changes of the gene expression profiling. After fenofibrate treatment, (A) the top ten most obvious changes in GO biological process classification confirmed that fenofibrate could induce apoptosis of MDA-MB-231 cells. (B) Cell cycle pathway ranked first in the top ten most significant down-regulated pathways. (C) p53 pathway ranked tenth in the top ten most significant up-regulated pathways.Back to article page