Table 5 Cox proportional univariate and multivariate analysis of the association between prognostic variables and overall and disease-free survival in cervical cancer
From: MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer
| Â | Disease-free Survival hazard ratio [95% CI], Pvalue | Overall Survival hazard ratio [95% CI], Pvalue | ||
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |
FIGO stage | 5.32 [2.75-10.30], <0.001 | 3.60 [1.36-9.55], 0.010 | 3.97 [1.65-9.54], 0.002 | 2.77 [1.13-7.76], 0.025 |
Tumor grade (poor) | 1.65 [0.85-3.22], 0.137 | NA | 2.15 [0.89-5.21], 0.087 | NA |
Tumor size (>4Â cm) | 2.13 [1.09-4.14], 0.025 | 1.16 [0.47-2.90], 0.737 | 1.90 [0.78-4.65], 0.157 | NA |
LN metastasis | 4.53 [2.14-9.61], <0.001 | 2.71 [1.08-6.79], 0.032 | 2.25 [0.77-6.59], 0.136 | NA |
HPV+ | 0.68 [0.08-5.21], 0.710 | NA | 0.38 [0.048-3.10], 0.370 | NA |
MICA/B+ | 0.43 [0.20-0.92], 0.032 | 0.54 [0.20-1.41], 0.213 | 0.53 [0.20-1.36], 0.189 | NA |
ULBP1+ | 0.36 [0.16-0.80], 0.012 | 0.31 [0.11-0.86], 0.024 | 0.21 [0.06-0.73], 0.014 | 0.27 [0.07-0.97], 0.044 |
RAET1E+ | 2.17 [1.12-4.2], 0.021 | 1.90 [0.84-4.32], 0.123 | 1.03 [0.41-2.60], 0.935 | NA |
RAET1G+ | 2.09 [1.05-4.15], 0.034 | 1.62 [0.68-3.87], 0.275 | 1.69 [0.70-4.09], 0.240 | NA |
MICA/B+/ULBP1+ | 0.11 [0.02-0.45], 0.002 | 0.16 [0.03-0.70], 0.015 | 0.026 [0.00-1.17], 0.060 | NA |