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Table 1 Characteristics of the included studies

From: The effects of psychological interventions on depression and anxiety among Chinese adults with cancer: a meta-analysis of randomized controlled studies

Author & years Age (Mean) Subjects (n1 + n2) Outcomes Patients’ selection Cancer type Cancer stage Intervention type Therapist Intervention format
Wang et al. 2000 [39] 18-67 38 + 38 Both (SDS,SAS) Nonselective Mixed - Doctor A
Zhao et al. 2000 [153] 22-67 (52) 42 + 41 Both (SDS,SAS) Nonselective Mixed Advanced  +  +  +  - A + B + C
Cai et al. 2001 [144] 26-70 (50.6) 116+ 46 Both (HAMD,SAS) Nonselective Mixed - - A + B
Yang et al. 2002 [42] 28-65 (44.6) 34 + 30 Depression (HAMD) Nonselective Mixed -  +  - B
Guan et al. 2002 [123] 30-71 44 + 44 Both (SDS,SAS) Nonselective Mixed -  +  +  +  Oncologist B
Li et al. 2002 [76] 32-71 (51.2) 61 + 47 Both (SDS,STAI) Nonselective Mixed Early  +  +  +  +  - A + B + C
Lian et al. 2003 [44] 18-65 (46) 50 + 50 Both (SDS,SAS) Nonselective Head/neck -  +  +  - -
Wu & Wang 2003 [148] 30-78 (56) 63 + 57 Both (SDS,SAS) Nonselective Lung Advanced  +  +  +  Doctor (training) A + B + C
Zhong et al. 2003 [38] >16 91 + 92 Both (SDS,SAS) Nonselective Mixed - - -
Lou et al. 2003 [101] 31-72 85 + 86 Depression (DSI) Nonselective Mixed -  +  +  Nurse A + C
Xu 2004 [115] 30-70 (58) 150 + 100 Both (SDS,SAS) Nonselective Digestive tract -  +  +  +  Nurse A + C
Wang 2004 [93] 36-65 30 + 22 Depression (SDS) Nonselective Breast -  +  +  +  Nurse A + C
Bu et al. 2005 [155] >18 (46.5) 30 + 30 Anxiety (SAS) Selective Digestive tract -  +  +  +  Nurse -
Lou et al. 2005 [164] 24-71 (58) 75 + 75 Anxiety (SAS) Nonselective Mixed -  +  +  +  - A + C
Liu et al. 2006 [143] 16-77 (51.9) 58 + 53 Both (SDS,STAI) Nonselective Mixed - - A
Cheng et al. 2006 [107] >16 (65.3) 15 + 15 Both (HAMD,HAMA) Nonselective Mixed Advanced  +  +  +  - -
Wang et al. 2006 [75] >18 (56.1) 31 + 31 Both (SDS,SAS) Nonselective Mixed Advanced  +  Nurse (training)/Oncologist B
Ni et al. 2007 [165] >18 (55.4) 169 + 157 Anxiety (SAS) Nonselective Mixed Advanced  +  +  +  Doctor A + C
Pang & Wang 2007 [166] 31-62 (59) 43 + 42 Anxiety (SAS) Nonselective Breast -  +  +  +  Nurse (training) A + C*
Qian & Cai 2007 [50] 18-65 40 + 40 Both (SDS,SAS) Nonselective Gynecology -  +  +  +  +  Nurse A + B + C
Wen & Liang 2007 [69] 16-40 73 + 63 Both (SDS,STAI) Nonselective Mixed -  +  +  +  - A + B
Kang 2007 [128] 40-60 30 + 30 Both (SDS,SAS) Nonselective Breast Advanced  +  - A + B
Zheng et al. 2007 [109] 39-86 (58) 35 + 35 Both (SDS,SAS) Selective Mixed -  +  +  +  Oncologist/Nurse A + C
Deng et al. 2007 [110] 32-70 (55.3) 60 + 60 Both (SDS,SAS) Nonselective Mixed -  +  +  Doctor A + C
Xing 2007 [103] 43-75 (57.2) 50 + 50 Both (SDS,SAS) Nonselective Gynecology -  +  +  +  - A + C
Wu et al. 2007 [59] 18-70 (48.4) 40 + 40 Both (SDS,SAS) Nonselective Mixed Advanced  +  +  +  +  Nurse A + B + C
Xu 2007 [88] 20-70 32 + 32 Both (SDS,SAS) Nonselective Gynecology -  +  +  +  Nurse A + B + C
Han & Liu 2007 [151] 27-76 (59.1) 30 + 30 Both (SDS,SAS) Nonselective Mixed -  +  +  +  Nurse A + B
Huang et al. 2008 [54] >16 40 + 40 Both (SDS,SAS) Nonselective Mixed -  +  +  +  +  Nurse A
Zheng et al. 2008 [116] >18 (58.9) 38 + 39 Both (SDS,SAS) Nonselective Mixed -  +  +  +  - A + C
Yang 2008 [79] >16 40 + 40 Both (SDS,SAS) Nonselective Gynecology -  +  +  +  Nurse A + C
Han 2008 [160] 33-65 (48.1) 32 + 35 Anxiety (SAS) Nonselective Breast -  +  +  +  Nurse A + C
Jiang et al. 2008 [161] 28-64 (52) 52 + 52 Anxiety (SAS) Nonselective Mixed - - A
Li et al. 2008 [163] 25-78 (53) 24 + 24 Anxiety (SAS) Nonselective Digestive tract - Nurse A
Wang et al. 2008 [169] >18 40 + 40 Anxiety (SAS) Nonselective Digestive tract Early  +  +  +  +  - -
Ji 2008 [106] 22-83 (54.2) 40 + 40 Depression (SDS) Nonselective Mixed -  +  +  +  Doctor/Nurse (training) A + B + C
Jin & Zhu 2008 [122] 42-65 (59) 30 + 30 Both (SDS,SAS) Nonselective Lung -  +  +  +  +  - A + B
Li et al. 2008 [99] 26-73 (43.7) 30 + 30 Both (SDS,SAS) Nonselective Digestive tract -  +  +  +  Nurse A + C
Liu et al. 2008 [52] 24-70 (50) 90 + 50 Both (SDS,SAS) Nonselective Gynecology -  +  +  - A + B + C
Yang 2008 [136] 18-70 (49.7) 31 + 31 Both (SDS,SAS) Nonselective Breast Early  +  +  +  Clinical psychologist B
Zhou 2008 [100] 26-57 32 + 32 Both (SDS,SAS) Nonselective Blood -  +  +  +  Nurse/Psychologist -
Mao et al. 2008 [113] >16 (55.3) 82 + 76 Both (HAMD,HAMA) Nonselective Mixed -  +  Nurse -
Liu 2008 [132] 25-72 31 + 31 Both (HAMD,HAMA) Nonselective Gynecology Advanced  +  - A
Zheng et al. 2008 [125] 18-70 (51.4) 50 + 50 Both (SDS,SAS) Nonselective Mixed Advanced  +  +  Nurse A
Chen et al. 2009 [156] >18 33 + 32 Anxiety (SAS) Selective Digestive tract -  +  +  +  +  +  Psychologist/Nurse (training) A
Li 2009 [89] 30-60 (46) 30 + 30 Both (SDS,SAS) Nonselective Gynecology -  +  +  +  - -
Li et al. 2009 [78] 22-84 78 + 78 Both (SDS,SAS) Nonselective Digestive tract -  +  +  Psychologist/Doctor/Nurse A + B + C
Fu et al. 2009 [145] 26-60 (39.3) 40 + 38 Both (SDS,SAS) Nonselective Breast Advanced - A
Qiu 2009 [133] 30-70 30 + 30 Both (SDS,SAS) Nonselective Lung -  +  +  - A
Sun 2009 [134] >18 (43.4) 30 + 30 Both (HASD) Nonselective Mixed -  +  - A
Xia 2009 [118] 24-60 (47) 28 + 28 Both (SDS,SAS) Selective Mixed -  +  +  +  Nurse (training) -
Zhang 2009 [139] 18-70 (55) 34 + 32 Depression (SDS) Selective Mixed -  +  +  - A
Zhou 2009 [140] 18-55 (45.9) 30 + 30 Both (SDS,SAS) Selective Breast Early - A
Li et al. 2009 [63] 18-72 (40.5) 61 + 59 Both (SDS,SAS) Nonselective Head/neck -  +  +  +  Psychologist B
Geng et al. 2010 [104] 23-82 124 + 123 Both (SDS,SAS) Nonselective Mixed -  +  +  + +  Researcher (training) A + C
Zhan & Cheng 2010 [105] 18-75 35 + 35 Both (SDS,SAS) Nonselective Lung Advanced  +  +  +  Doctor/Nurse (training) A + B + C
Cheng et al. 2010 [45] 21-69 (47) 50 + 50 Both (SDS,SAS) Nonselective Head/neck -  +  +  +  Oncologist/Psychologist/Nurse A + B + C
Li et al. 2010 [91] 41-68 (52.2) 50 + 50 Both (SDS,SAS) Nonselective Gynecology -  +  +  Nurse -
Guan et al. 2010 [81] 38-70 (44) 30 + 30 Both (SDS,SAS) Nonselective Urinary -  +  +  Nurse -
Li 2010 [111] 31-72 (49.7) 57 + 57 Both (SDS,SAS) Nonselective Mixed Advanced  +  Doctor/Nurse A + B + C
Zhang 2010 [138] >18 (49.7) 47 + 48 Both (SDS,SAS) Nonselective Breast Early ++ - B
Su & Wang 2010 [167] >18 (52.9) 41 + 46 Anxiety (SAS) Selective Digestive tract - +++ Nurse (training) A + C
Fu et al. 2010 [159] 27-64 (46.5) 36 + 28 Anxiety (SAS) Nonselective Mixed Advanced + + + +  - A + C
Wu & Zhang 2010 [170] 30-75 (48) 40 + 39 Anxiety (SAI) Nonselective Digestive tract Advanced  +  +  +  +  Nurse -
Zhou 2010 [176] 30-65 60 + 60 Anxiety (SAS) Nonselective Breast -  +  +  +  +  Nurse -
You et al. 2010 [171] >18 (48.9) 33 + 29 Anxiety (SAS) Nonselective Breast - + Nurse A
Ren et al. 2010 [154] 33-74 (54.2) 40 + 37 Both (SDS,SAS) Nonselective Mixed -  +  +  - A + B + C
Xu 2010 [40] 27-73 (51) 47 + 43 Both (SDS,SAS) Selective Mixed - +  +  Nurse A
Guo et al. 2010 [71] 23-82 (45.4) 45 + 45 Both (SDS,SAS) Nonselective Mixed Advanced + Researcher (cognitive therapy training) A
Tang et al. 2010 [126] >18 (49.8) 40 + 40 Both (SDS,SAS) Nonselective Breast - + + + Nurse A + C
Liu et al. 2010 [46] >16 (51.1) 50 + 50 Both (SDS,SAS) Nonselective Mixed -  +  Nurse (training) -
Shi et al. 2010 [108] 21-79 (54) 20 + 20 Depression (HAMD) Selective Digestive tract Advanced  +  Psychologist A + B
Liu et al. 2010 [87] >16 (57.5) 37 + 35 Both (SDS,SAS) Nonselective Lung Early + Psychologist A + B + C
Wang 2010 [90] >16 (48.1) 43 + 43 Both (SDS,SAS) Nonselective Gynecology - + + + + - A + B
Huang et al. 2010 [86] >16 (63.6) 32 + 28 Both (SDS,SAS) Nonselective Lung - +  +  +  - -
Zhang & Yu 2011 [94] 21-53 60 + 60 Both (SDS,SAS) Nonselective Breast - + + + - A + C
Du et al. 2011 [61] >16 (42.7) 28 + 30 Both (SDS,SAS) Nonselective Breast - Nurse A
Li et al. 2011 [149] >18 (47) 20 + 20 Both (SDS,SAS) Selective Gynecology - + + + + - A
Zhou et al. 2011 [180] 25-65 (45) 54 + 51 Depression (SDS) Nonselective Breast - - A
Liu 2011 [131] 23-65 30 + 30 Both (SDS,SAS) Selective Gynecology - +++ - A + C
Shen et al. 2011 [64] 39-71 (58.1) 37 + 38 Both (SDS,SAS) Nonselective Digestive tract - + Nurse A
Zhu et al. 2011 [65] >60 (74) 50 + 48 Depression (SDS) Nonselective Digestive tract - + + + Nurse A + B
Meng et al. 2011 [95] 34-74 (57) 46 + 41 Both (SDS,SAS) Nonselective Mixed Advanced +  +  + Nurse -
Dai et al. 2011 [157] 23-78 (57.9) 66 + 68 Anxiety (SAI) Nonselective Mixed - + + + + Oncologist/Psychologist/Nurse/Nutritionist B
Jiao et al. 2011 [162] 40-66 (55.8) 34 + 34 Anxiety (SAS) Nonselective Gynecology Advanced + + + + Nurse (training) A + C
Ye 2011 [56] 24-65 (43.5) 20 + 20 Both (SDS,SAS) Selective Gynecology - + - A
Li 2011 [130] 18-80 37 + 32 Depression (SDS) Nonselective Digestive tract Early + + + + + + - A + B + C
Liu et al. 2011 [41] 30-50 50 + 50 Depression (SDS) Nonselective Mixed - +  +  Medical staff A + B
Wang et al. 2011 [37] >16 (59.03) 30 + 31 Both (HAMD,HAMA) Nonselective Mixed - Psychologist B
Cao2011 [173] >18 30 + 30 Anxiety (SAS) Nonselective Breast - Nurse (psychological/music training) A
Zhao & Zhang 2011 [174] 18-70 21 + 20 Anxiety (SAS) Selective Gynecology - + + + + Nurse A + C
Cao & Li 2011 [67] >16 55 + 53 Both (SDS,SAS) Nonselective Mixed - - A + B + C
Huang et al. 2011 [152] 33-71 140 + 139 Depression (SDS) Nonselective Mixed - +  +  Nurse (training) A + B + C
Hu & Yan 2011 [62] 30-52 (45) 32 + 32 Both (SDS,SAS) Nonselective Mixed -  +  Psychologist/Oncologist/Nurse (training) B
Guan & Jin 2011 [120] 18-75 (66) 78 + 78 Both (SDS,SAS) Nonselective Mixed Advanced + + + + + - A + C
Lv et al. 2011 [77] 25-65 38 + 38 Both (SDS,SAS) Nonselective Gynecology Early + + + Nurse A + B
Li et al. 2011 [182] 25-65 (45) 54 + 51 Anxiety (SAI) Nonselective Breast - - A
Cao & Jiang 2011 [177] >18 (51.5) 42 + 42 Anxiety (SAS) Nonselective Lung - + + + Nurse A + B + C
Huang2011 [102] >16 (54.23) 40 + 40 Depression (HAMD) Selective Mixed - + +  +  - A + B
Zheng et al. 2011 [141] 21-81 (54) 102 + 111 Both (SDS,SAS) Nonselective Mixed - ++ Nurse A + B + C
Wu & Dong 2011 [47] 48-78 (63.3) 33 + 33 Both (HAMD,HAMA) Selective Mixed - + +  +  - A + C
Zheng et al. 2012 [150] 19-70 (52.6) 28 + 28 Depression (SDS) Selective Mixed - +  +  Doctor A + C
Wang & Xiao 2012 [124] >18 (57.5) 42 + 42 Both (SDS,SAS) Nonselective Mixed - +  +  Psychologist A
Wei 2012 [135] >18 (48.1) 30 + 30 Both (SDS,SAS) Nonselective Breast - + +  +  - A + B
Feng 2012 [55] 35-65 (50.9) 45 + 45 Both (SDS,SAS) Nonselective Breast - +  +  - A
Yang et al. 2012 [73] 48-81 20 + 20 Both (SDS,SAS) Nonselective Breast Advanced + + + Psychologist A + B + C
Zhao et al. 2012 [84] 18-75 (57.2) 103 + 102 Both (SDS,SAS) Nonselective Mixed - +  +  Doctor -
Gu 2012 [121] 47-74 (64.6) 52 + 48 Both (SDS,SAS) Nonselective Lung - + + Nurse A + C
Zheng2012 [58] 45-72 (51.6) 30 + 30 Both (HAMD,HAMA) Selective Mixed - +  +  - -
Yang2012 [66] 59-76 (65.4) 23 + 20 Depression (SDS) Selective Digestive tract - ++ Nurse A + C
Sun et al. 2012 [60] 21-78 (49.4) 89 + 89 Both (SDS,SAS) Nonselective Mixed - + + + Psychologist/Nurse A + B + C
Liu et al. 2012 [98] >18 (48.6) 30 + 30 Both (SDS,SAS) Nonselective Digestive tract - + + - A + C
Yang et al. 2012 [70] 20-70 (58.4) 48 + 40 Both (SDS,SAS) Nonselective Mixed Advanced  +  +  Nurse -
Li 2012 [129] 34-36 (41.7) 51 + 51 Both (CES-D,SAI) Nonselective Mixed -  +  Nurse A
Zhu & Hu 2012 [68] 23-76 (44.3) 45 + 46 Both (SDS,SAS) Nonselective Gynecology - ++ Nurse (training) A + B + C
Liu 2012 [48] 45-74 (62.3) 40 + 40 Depression (HAMD) Nonselective Mixed - + + + Nurse A + C
Shi et al. 2012 [92] 21-65 (53.5) 74 + 74 Both (SDS,SAS) Nonselective Gynecology - +  +  - A
Jia2012 [127] 43-77 (55.8) 35 + 32 Both (HAMD,HAMA) Nonselective Head/neck - + + + + - A + C
Zhang 2012 [97] 34-71 (63.5) 45 + 45 Both (SDS,SAS) Nonselective Mixed Advanced  +  - -
Chen 2012 [51] 18-79 (51) 43 + 44 Both (SDS,SAS) Nonselective Gynecology - + +  +  - A + C
Li et al. 2012 [146] >18 (57.2) 30 + 30 Both (HAMD,HAMA) Nonselective Head/neck - + +  +  Doctor (training)/Psychologist A
Yang & Wang 2012 [83] 29-69 30 + 30 Both (HAMD,HAMA) Nonselective Mixed Advanced + + + + - A + C
Jiang et al. 2012 [49] >16 44 + 45 Depression (SDS) Nonselective Head/neck - + + Nurse A
Fan & Pan 2012 [158] 30-48 19 + 19 Anxiety (SAS) Selective Gynecology -  +  + + - A + C
Li et al. 2012 [72] 24.5-70 50 + 50 Both (SDS,SAS) Nonselective Breast - + + Nurse A + B + C*
Han et al. 2012 [85] 18-91 (74) 43 + 42 Both (SDS,SAS) Nonselective Mixed - + + + Doctor/Nurse (training) A + C
Zheng et al. 2012 [175] 25-69 (46.5) 30 + 30 Anxiety (SAS) Nonselective Mixed - + + + + - A + C
Yuan & Wu 2013 [147] 50-70 (63) 78 + 78 Both (SDS,SAS) Nonselective Mixed Advanced  +  - A + C
Zhu et al. 2013 [36] 43-78 25 + 25 Both (SDS,SAS) Nonselective Lung - - -
Du 2013 [74] 24-76 (46.3) 36 + 36 Both (SDS,SAS) Nonselective Gynecology - +  +  Nurse/Community Doctor A + B + C*
Mu et al. 2012 [178] 32-70 (56.2) 60 + 60 Anxiety (SAS) Nonselective Urinary - + + + + Nurse A + B + C
Liu & Gan 2013 [43] 18-67 (49.3) 101 + 90 Both (SDS,STAI) Nonselective Mixed - - A
Zhang 2013 [96] 32-73 72 + 72 Both (SDS,SAS) Nonselective Mixed Advanced + + + + - A + C
Zhang et al. 2013 [142] 32-72 (54) 33 + 35 Both (SDS,SAS) Nonselective Mixed -  +  +  Doctor (training) B
Guo et al. 2013 [179] >18 (47) 89 + 89 Both (SDS,SAS) Nonselective Mixed - + + Clinician/Nurse/Radiation therapist (training) B
Liu 2013 [119] 31-65 (53.3) 45 + 45 Both (SDS,SAS) Selective Mixed -  +  Nurse A
Zhai et al. 2013 [82] 47-62 (52) 39 + 39 Both (SDS,SAS) Nonselective Head/neck - + + + Nurse A + C
Ci et al. 2013 [117] 25-65 30 + 30 Both (SDS,SAS) Nonselective Mixed -  +  Nurse A + C
Liu 2013 [112] 46-71 (51.4) 59 + 59 Both (SDS,SAS) Selective Mixed -  +  - A + C
Liu et al. 2013 [57] 35-76 (53) 29 + 29 Both (SDS,SAS) Nonselective Bone metastatic - + + + + Nurse -
Qiu et al. 2013 [181] 31-64 (50.6) 29 + 25 Both (HAMD,SAS) Selective Breast Early Psychiatrist (CBT and group therapy training) B
Mao et al. 2013 [80] >16 (58.2) 100 + 100 Both (SDS,SAS) Nonselective Mixed - + + + + Psychologist A + C
Zhang 2013 [114] 18-70 (46) 53 + 53 Both (SDS,SAS) Nonselective Gynecology - + + + + Nurse A + C
Yu 2013 [137] >18 79 + 41 Both (SDS,SAS) Nonselective Head/neck - + + Doctor A + B + C
Wang 2013 [53] 21-70 (45) 50 + 50 Both (SDS,SAS) Nonselective Gynecology - + + Nurse A + C
Tian et al. 2013 [168] >18 (61.1) 98 + 97 Anxiety (SAS) Nonselective Mixed - + + + Nurse A + C
Yu 2013 [172] 33-61 (41.9) 83 + 83 Anxiety (SAS) Nonselective Breast - + + - A + C*
  1. Abbreviations: n1 participants in experimental group, n2 participants in control group, SDS Self-rating Depression Scale, SAS Self-rating Anxiety Scale, HAMD Hamilton Depression Rating Scale, HAMA Hamilton Anxiety Rating Scale, STAI State-Trait Anxiety Inventory, DSI Depression Screening Instrument, CES-D Center for Epidemiologic Studies Depression Scale, SAI State Anxiety Inventory, HASD Hospital Anxiety and Depression Scale, cognitive-behavioral interventions, patients education, relaxation/imagery, social/family support, music therapy, nursing intervention, other interventions, A individual, B Group, C Family, C* Couple, no report.