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Table 2 Response Rates to NC incorporating trastuzumab

From: Anthracycline-free neoadjuvant therapy induces pathological complete responses by exploiting immune proficiency in HER2+ breast cancer patients

  N PD cPR cCR tpCR bpCR
Total 46 (100%) 2 (4.4%) 23 (50%) 21 (45.6%) 23 (50%) 26 (56.5%)
ER status       
Positive 22 (47.8%)   13 (59%) 9 (41%) 10 (45.4%) 12 (54.5%)
Negative 24 (52.2%) 2 (8.3%) 10 (41.7%) 12 (50%) 13 (54.2%) 14 (58.3%)
Stage distribution       
IIA 6 (13%) 1(16.6%) 4 (66.8%) 1 (16.6%) 5 (83%) 5 (83%)
IIB 27 (58.7%)   13 (48%) 14 (52%) 11 (41%) 14 (52%)
IIIA 12 (26.1%) 1 (8.3%) 5 (41.7%) 6 (50%) 7 (58.3%) 7 (58.3%)
IIIB 1 (2.2%)   1 (100%)    
  1. Abbreviations: PD = progression disease; cPR = clinical partial response; cCR = clinical complete response; tpCR = total pathological complete response; bpCR = breast pathological complete response.