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Table 5 Incremental cost-effectiveness ratio (expressed in euros per QALY) in the univariate analysis

From: Cost-utility analysis of maintenance therapy with gemcitabine or erlotinib vsobservation with predefined second-line treatment after cisplatin–gemcitabine induction chemotherapy for advanced NSCLC: IFCT-GFPC 0502-Eco phase III study

Parameter value

Gemcitabine (n = 154)

Erlotinib (n = 155)

Base case

76,625

184,733

Gemcitabine tariff

  

 –30%

47,132

Erlotinib tariff

  

 –30%

125,957

Pemetrexed tariff

  

 –30%

79,749

188,212

Palliative care cost

  

 €1,627 per month

81,021

183,772

 €3,021 per month

72,213

185,680

Utility score under observation

  

 –10%

117,197

307 149

 +10%

57,136

130,727

Utility score under IV chemotherapy

  

 –10%

€117,197

 +10%

€57,136

Utility score under oral chemotherapy

  

 –10%

€366,092

 +10%

€124,060

  1. Incremental cost-effectiveness ratios (ICER) are expressed in euros/quality adjusted-life years (QALY). The sign “-” was used when the ICER was not affected by the univariate analysis.
  2. Legend: IV: intravenous.