Skip to main content

Table 2 Association of COX-2 immunostaining status (intensity 3 vs 0-2) with breast cancer specific disease-free survival (DFS) in the Mainz cohort of node negative breast cancer patients (n = 193)

From: Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patients

A. Univariate Cox analysis

Prognostic factor

p

HR

95% CI

COX-2 immunostaining status

0.001

2.427

1.426-4.131

B. Multivariate Cox analysis

Prognostic factors

p

HR

95% CI

Age

0.467

0.802

0.443-1.452

(<50 vs ≥50 years)

pT stage

0.815

1.068

0.614-1.861

(≤2cm vs >2cm)

Histological grade

   

(Grade 3 vs grade 1 and 2)

<0.001

4.510

2.562-7.940

HR1 (ER or PR)

0.523

0.813

0.431-1534

(negative vs. positive)

HER-2 status

0.498

1.273

0.633-2.559

(positive vs negative)

COX-2 immunostaining status

<0.001

2.767

1.563-4.901

  1. 1The hormone receptor status (HR) is positive as soon as one of both, the estrogen (ER) or the progesterone receptor status (PR), is positive.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us