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Table 2 Patients planned for adjuvant chemotherapy, younger than 76 years with stage III colon cancer by patient and health-care region (n = 3427)

From: A population-based cohort study on adherence to practice guidelines for adjuvant chemotherapy in colorectal cancer

  Univariate Multivariate
  OR 95% CI OR 95% CI P
Gender      
Male 1.00   1.00   
Female 1.36 1.13-1.65 1.29 1.04-1.61 0.021
Age (years)      
60-75 1.00   1.00   
<60 2.65 2.02-3.55 2.14 1.57-2.98 <0.01
ASA classification*      
3-4 1.00   1.00   
1-2 4.31 3.51-5.28 4.26 3.14-5.33 <0.01
N-stage      
1a 1.00   1.00   
1b 1.29 1.01-1.66 1.20 0.92-1.57  
2 1.64 1.29-2.08 1.62 1.24-2.12 <0.01
Tumor differentiation      
Low-grade (G1, G2) 1.00   1.00   
High-grade (G3, G4) 0.94 0.76-1.17 0.84 0.66-1.08 0.17
Planned surgery      
Yes 1.00   1.00   
No 0.79 0.63-0.99 0.83 0.64-1.09 0.18
Multidisciplinary conference      
No 1.00   1.00   
Yes 1.78 1.44-2.21 1.83 1.41-2.37 <0.01
Region      
Northern 1.00   1.00   
Stockholm-Gotland 1.29 0.89-1.84 0.96 0.63-1.46  
Uppsala-Örebro 1.45 1.02-2.05 1.14 0.75-1.71  
Southeastern 1.10 0.74-1.63 0.89 0.56-1.40  
Southern 1.33 0.92-1.89 1.17 0.76-1.79  
Western 1.16 0.82-1.64 0.95 0.63-1.42 0.67
  1. Complete case univariate and multivariate logistic regression.
  2. Abbreviation: OR, Odds Ratio. *American Society of Anesthesiologists Physical Status Classification System. TNM, 7th edition from UICC/AJCC (Union for International Cancer Control/American Joint Committee on Cancert). Statistical method; Wald test.