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Table 2 Patients planned for adjuvant chemotherapy, younger than 76 years with stage III colon cancer by patient and health-care region (n = 3427)

From: A population-based cohort study on adherence to practice guidelines for adjuvant chemotherapy in colorectal cancer

 

Univariate

Multivariate

 

OR

95% CI

OR

95% CI

P

Gender

     

Male

1.00

 

1.00

  

Female

1.36

1.13-1.65

1.29

1.04-1.61

0.021

Age (years)

     

60-75

1.00

 

1.00

  

<60

2.65

2.02-3.55

2.14

1.57-2.98

<0.01

ASA classification*

     

3-4

1.00

 

1.00

  

1-2

4.31

3.51-5.28

4.26

3.14-5.33

<0.01

N-stage

     

1a

1.00

 

1.00

  

1b

1.29

1.01-1.66

1.20

0.92-1.57

 

2

1.64

1.29-2.08

1.62

1.24-2.12

<0.01

Tumor differentiation

     

Low-grade (G1, G2)

1.00

 

1.00

  

High-grade (G3, G4)

0.94

0.76-1.17

0.84

0.66-1.08

0.17

Planned surgery

     

Yes

1.00

 

1.00

  

No

0.79

0.63-0.99

0.83

0.64-1.09

0.18

Multidisciplinary conference

     

No

1.00

 

1.00

  

Yes

1.78

1.44-2.21

1.83

1.41-2.37

<0.01

Region

     

Northern

1.00

 

1.00

  

Stockholm-Gotland

1.29

0.89-1.84

0.96

0.63-1.46

 

Uppsala-Örebro

1.45

1.02-2.05

1.14

0.75-1.71

 

Southeastern

1.10

0.74-1.63

0.89

0.56-1.40

 

Southern

1.33

0.92-1.89

1.17

0.76-1.79

 

Western

1.16

0.82-1.64

0.95

0.63-1.42

0.67

  1. Complete case univariate and multivariate logistic regression.
  2. Abbreviation: OR, Odds Ratio. *American Society of Anesthesiologists Physical Status Classification System. TNM, 7th edition from UICC/AJCC (Union for International Cancer Control/American Joint Committee on Cancert). Statistical method; Wald test.