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Table 3 Variables associated with RECIST defined response to CTX

From: Metronomic oral cyclophosphamide (MOC) in the salvage therapy of heavily treated recurrent ovarian cancer patients: a retrospective, multicenter study

  

Clinical response

p valuea

Variable

All cases N.

Complete and Partial response N. (%)

Stable and Progressive disease N. (%)

 

GCIG response

    

Complete/Partial

16

9 (56.2)

7 (43.7)

 

SD/Progression

35

0

35 (100)

0.0001 b

Histotype

    

Serous

45

7 (15.5)

38 (84.4)

 

Other

9

4 (44.4)

5 (55.5)

0.07

Pattern of recurrence

    

Carcinomatosis

43

9 (20.9)

34 (79.1)

 

Isolated lymph node or parenchymal disease

11

2 (18.2)

9 (81.8)

0.69

Platinum sensitivity

    

Refractory/resistant

20

3 (15.0)

17 (85.0)

 

Sensitive

34

8 (23.5)

26 (76.5)

0.51

No. previous chemotherapy lines

    

≤4

34

7 (20.6)

27 (79.4)

 

>4

20

4 (20.0)

16 (80.0)

0.38

  1. aCalculated by Fisher’s exact test for proportion, bCalculated on 51 cases with baseline Ca125 levels > 35 I.U./ml.
  2. Percentages may not total 100% due to rounding.