Table 4 Risk of SPC by first and second cancer site among male patients, France 1989–2004 (N = 160,807)
From: The effect of patient characteristics on second primary cancer risk in France
First cancer site | Second cancer site | O | E | PYR | SIRa | EARa,b | (95% CI) |
|---|---|---|---|---|---|---|---|
Lip | Lung, bronchus and trachea | 27 | 9.52 | 4,081 | 2.84 | 42.8 | (20.3-72.9) |
Oesophagus | 7 | 1.79 | 3.91 | 12.8 | (2.5-31.0) | ||
Head and neck | Lung, bronchus and trachea | 663 | 76.15 | 38,731 | 8.71 | 151.5 | (138.7-165.1) |
Head and neckc | 405 | 24.54 | 16.50 | 98.2 | (88.3-108.9) | ||
Oesophagus | 269 | 13.79 | 19.51 | 65.9 | (57.8-74.7) | ||
Larynx | 76 | 10.74 | 7.07 | 16.8 | (12.7-21.8) | ||
Colorectum | 109 | 60.09 | 1.81 | 12.6 | (7.6-18.4) | ||
Liver, primary | 62 | 17.04 | 3.64 | 11.6 | (7.9-16.1) | ||
Bladder | 53 | 24.13 | 2.20 | 7.5 | (4.0-11.7) | ||
Kidney | 35 | 17.32 | 2.02 | 4.6 | (1.8-8.1) | ||
Pancreas | 26 | 11.03 | 2.36 | 3.9 | (1.5-7.0) | ||
Stomach | 29 | 14.27 | 2.03 | 3.8 | (1.3-7.1) | ||
Oesophagus | Head and neck | 92 | 6.29 | 7,367 | 14.63 | 116.3 | (92.1-144.6) |
Lung, bronchus and trachea | 71 | 16.70 | 4.25 | 73.7 | (52.6-98.9) | ||
Larynx | 16 | 2.25 | 7.11 | 18.7 | (9.4-32.2) | ||
Colorectum | 25 | 14.51 | 1.72 | 14.2 | (2.3-30.4) | ||
Stomach | 10 | 3.72 | 2.69 | 8.5 | (1.5-19.9) | ||
Bladder | 12 | 5.96 | 2.01 | 8.2 | (0.3-20.4) | ||
Colorectum | Colorectumc | 174 | 119.63 | 97,268 | 1.45 | 5.6 | (3.0-8.5) |
Lung, bronchus and trachea | 279 | 240.30 | 1.16 | 4.0 | (0.7-7.5) | ||
Bladder | 136 | 104.92 | 1.30 | 3.2 | (0.9-5.8) | ||
Larynx | Lung, bronchus and trachea | 310 | 44.71 | 19,900 | 6.93 | 133.3 | (116.5-151.7) |
Head and neck | 138 | 15.78 | 8.75 | 61.4 | (50.3-74.0) | ||
Oesophagus | 64 | 7.59 | 8.43 | 28.3 | (21.0-37.3) | ||
Bladder | 46 | 16.25 | 2.83 | 15.0 | (8.8-22.7) | ||
Colorectum | 62 | 39.40 | 1.57 | 11.4 | (4.1-20.1) | ||
Liver, primary | 22 | 10.72 | 2.05 | 5.7 | (1.5-11.4) | ||
Stomach | 19 | 9.27 | 2.05 | 4.9 | (1.1-10.3) | ||
Pancreas | 14 | 6.96 | 2.01 | 3.5 | (0.3-8.3) | ||
Lung, bronchus and trachea | Head and neck | 127 | 31.83 | 41,162 | 3.99 | 23.1 | (18.0-29.0) |
Bladder | 105 | 34.29 | 3.06 | 17.2 | (12.5-22.5) | ||
Oesophagus | 55 | 15.65 | 3.51 | 9.6 | (6.3-13.6) | ||
Colorectum | 121 | 84.25 | 1.44 | 8.9 | (3.9-14.7) | ||
Larynx | 45 | 12.08 | 3.73 | 8.0 | (5.0-11.7) | ||
Kidney | 45 | 21.47 | 2.10 | 5.7 | (2.8-9.4) | ||
Leukaemia | 30 | 16.07 | 1.87 | 3.4 | (1.0-6.5) | ||
Melanoma of skin | Leukaemia | 19 | 6.22 | 20,881 | 3.06 | 6.1 | (2.5-11.2) |
Prostate | Colorectum | 830 | 692.73 | 230,582 | 1.20 | 6.0 | (3.5-8.5) |
Bladder | 406 | 291.02 | 1.40 | 5.0 | (3.3-6.8) | ||
Testis | Kidney | 10 | 2.38 | 19,448 | 4.20 | 3.9 | (1.2-8.2) |
Bladder | Lung, bronchus and trachea | 295 | 94.45 | 38,002 | 3.12 | 52.8 | (44.2-62.2) |
Prostate | 398 | 257.66 | 1.54 | 36.9 | (26.9-47.7) | ||
Head and neck | 55 | 27.02 | 2.04 | 7.4 | (3.8-11.7) | ||
Larynx | 28 | 10.96 | 2.55 | 4.5 | (2.0-7.8) | ||
Stomach | 38 | 23.71 | 1.60 | 3.8 | (0.8-7.5) | ||
Kidney | Prostate | 269 | 162.00 | 28,385 | 1.66 | 37.7 | (26.7-49.7) |
Bladder | 39 | 24.55 | 1.59 | 5.1 | (1.1-10.1) | ||
Thyroid gland | Prostate | 34 | 20.08 | 7,369 | 1.69 | 18.9 | (4.7-37.2) |
Leukaemia | 5 | 1.50 | 3.33 | 4.7 | (0.1-13.8) | ||
Hodgkin's disease | Lung, bronchus and trachea | 23 | 5.72 | 8,338 | 4.02 | 20.7 | (10.6-34.5) |
Non-Hodgkin’s lymphoma | 6 | 1.33 | 4.50 | 5.6 | (1.0-14.1) | ||
Oesophagus | 4 | 0.93 | 4.29 | 3.7 | (0.2-11.2) | ||
Non-Hodgkin’s lymphoma | Lung, bronchus and trachea | 76 | 46.84 | 26,008 | 1.62 | 11.2 | (5.0-18.6) |
Leukaemia | 21 | 8.50 | 2.47 | 4.8 | (1.7-9.1) | ||
Bladder | 30 | 17.70 | 1.70 | 4.7 | (1.0-9.7) | ||
Stomach | 18 | 10.21 | 1.76 | 3.0 | (0.2-7.0) | ||
Chronic lymphatic leukaemia | Lung, bronchus and trachea | 56 | 27.69 | 11,261 | 2.02 | 25.1 | (13.0-40.0) |
Colorectum | 41 | 27.78 | 1.48 | 11.7 | (1.5-24.7) | ||
Hodgkin’s disease | 4 | 0.39 | 10.26 | 3.2 | (0.6-8.7) |