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Table 2 Expression of different endothelial markers by the three cell lines isolated in the study

From: Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib

  Cell lines  
  PTEC1 PTEC2 PTEC3 AVERAGE
Isotype 5.32 ± 0.57 6.34 ± 0.77 5.69 ± 0.98 5.783 ± 0.83
CD146 6.598 ± 1.08 12.203 ± 2.87 14.727 ± 9.89 11.176 ± 4.93
CD105 91.614 ± 28.56 70.547 ± 17.45 65.707 ± 26.94 75.956 ± 19.62
CD31 27.942 ± 3.75 30.723 ± 4.46 24.54 ± 7.92 28.068 ± 5.89
TIE-2 23.555 ± 2.46 19.973 ± 4.77 29.13 ± 4.04 24.219 ± 4.84
VEGFR1 19.954 ± 5.35 8.68 ± 4.67 12.17 ± 2.78 13.575 ± 5.94
VEGFR2 20.782 ± 3.07 18.545 ± 3.71 25.83 ± 17.55 21.719 ± 8.32
VEGFR3 5.057 ± 2.69 7.811 ± 2.44 10.603 ± 3.92 7.823 ± 3.16
  1. Levels of endothelial markers was detected by cytofluorimetric analysis after cell staining with a specific conjugated Abs. An irrelevant isotypic Ab (isotype) was used as control of aspecific binding. Data represent the median fluorescent intensity (MFI ± SD) detected on the cell isolates at all culture passages used (1–6). All markers were significantly different versus isotypic control (p < 0.001), as evaluated using the Kolmogorov-Smirnov statistical analysis.