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Table 2 Expression of different endothelial markers by the three cell lines isolated in the study

From: Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib

 

Cell lines

 
 

PTEC1

PTEC2

PTEC3

AVERAGE

Isotype

5.32 ± 0.57

6.34 ± 0.77

5.69 ± 0.98

5.783 ± 0.83

CD146

6.598 ± 1.08

12.203 ± 2.87

14.727 ± 9.89

11.176 ± 4.93

CD105

91.614 ± 28.56

70.547 ± 17.45

65.707 ± 26.94

75.956 ± 19.62

CD31

27.942 ± 3.75

30.723 ± 4.46

24.54 ± 7.92

28.068 ± 5.89

TIE-2

23.555 ± 2.46

19.973 ± 4.77

29.13 ± 4.04

24.219 ± 4.84

VEGFR1

19.954 ± 5.35

8.68 ± 4.67

12.17 ± 2.78

13.575 ± 5.94

VEGFR2

20.782 ± 3.07

18.545 ± 3.71

25.83 ± 17.55

21.719 ± 8.32

VEGFR3

5.057 ± 2.69

7.811 ± 2.44

10.603 ± 3.92

7.823 ± 3.16

  1. Levels of endothelial markers was detected by cytofluorimetric analysis after cell staining with a specific conjugated Abs. An irrelevant isotypic Ab (isotype) was used as control of aspecific binding. Data represent the median fluorescent intensity (MFI ± SD) detected on the cell isolates at all culture passages used (1–6). All markers were significantly different versus isotypic control (p < 0.001), as evaluated using the Kolmogorov-Smirnov statistical analysis.
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BMC Cancer

ISSN: 1471-2407

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