Figure 3
From: Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib
Wound healing migration in PTEC lines. (A): percentage of migration of PTEC after treatment with 1 μM Sunitinib or 1 μM Sorafenib compared to positive control. (B): representative images of PTEC migration at time 0 and 8 hours. (C): quantification of relative cell migration at 8 hours for the three PTEC cell lines. 1 μM Sunitinib showed a higher inhibition of cell migration compared to 1 μM Sorafenib. Data are expressed as mean ± S.E.M of three independent experiments performed with PTEC1, 2 and 3 and migration was normalized to control: Statistical significance *p < 0.05.