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Figure 1 | BMC Cancer

Figure 1

From: LEIGClong non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition

Figure 1

Alterations in lncRNA expression profiles between gastric tumor tissues and paired adjacent non-tumorous tissues. (A). lncRNA expression was evaluated by an lncRNA expression microarray. Results from hierarchical clustering showed different lncRNA expression among samples. ā€œRedā€ indicates high expression; ā€œgreenā€ indicates low expression. (B). Results from qRT-PCR experiments demonstrating downregulated expression of lncRNAs in three gastric cancer samples. (C). qRT-PCR analysis of lncRNAs selected from microarray results in three gastric cancer samples revealed upregulated expression. (D). qRT-PCR verification of mRNA selected from microarray results in three gastric cancer samples. (E). Expression of lncRNA LEIGC in fresh gastric cancer tissues from 35 patients was detected by qRT-PCR. LEIGC levels were normalized to GAPDH and expressed in terms of the threshold cycle (CT) ratio. Error bars represent the meansā€‰Ā±ā€‰SEM. *Pā€‰<ā€‰0.05; **Pā€‰<ā€‰0.01.

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