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Table 4 Overall survival (univariate analysis)

From: Radiosurgery alone versus radiosurgery plus whole-brain irradiation for very few cerebral metastases from lung cancer

  At 6 months At 12 months P-value
Treatment approach    
 Radiosurgery alone (n = 98) 68 49  
 Radiosurgery + WBI (n = 50) 78 59 0.32
Radiosurgery dose    
 <20 Gy (n = 63) 75 51  
 ≥20 Gy (n = 85) 69 54 0.45
Age    
 ≤59 years (n = 76) 74 63  
 ≥60 years (n = 72) 69 41 0.10
Gender    
 Female (n = 68) 82 61  
 Male (n = 80) 63 46 0.16
ECOG Performance Score    
 0-1 (n = 93) 76 61  
 2 (n = 55) 64 38 <0.001
Histology    
 Adenocarcinoma (n = 92) 76 64  
 Others (n = 56) 64 33 0.10
Number of cerebral metastases    
 1 (n = 90) 74 54  
 2-3 (n = 58) 67 50 0.51
Maximum diameter of all cerebral metastases    
 ≤18 mm (n = 75) 77 62  
 ≥19 mm (n = 73) 66 42 0.003
Main site of cerebral metastases    
 Supratentorial (n = 127) 72 53  
 Infratentorial (n = 21) 67 51 0.72
Extra-cerebral metastases    
 No (n = 95) 86 67  
 Yes (n = 53) 45 28 <0.001
Interval from lung cancer diagnosis to irradiation    
 ≤11 months (n = 77) 64 47  
 ≥12 months (n = 71) 80 59 0.060
  1. Significant p-values are given in bold.