Skip to main content

Table 3 Distant intra-cerebral control (univariate analysis)

From: Radiosurgery alone versus radiosurgery plus whole-brain irradiation for very few cerebral metastases from lung cancer

  At 6 months At 12 months P-value
Treatment approach    
 Radiosurgery alone (n = 98) 68 48  
 Radiosurgery + WBI (n = 50) 96 83 < 0.001
Radiosurgery dose    
 <20 Gy (n = 63) 72 63  
 ≥20 Gy (n = 85) 82 59 0.92
Age    
 ≤59 years (n = 76) 79 61  
 ≥60 years (n = 72) 75 61 0.88
Gender    
 Female (n = 68) 80 57  
 Male (n = 80) 75 64 0.52
ECOG Performance Score    
 0-1 (n = 93) 77 61  
 2 (n = 55) 79 61 0.84
Histology    
 Adenocarcinoma (n = 92) 76 56  
 Others (n = 56) 81 71 0.17
Number of cerebral metastases    
 1 (n = 90) 81 72  
 2-3 (n = 58) 73 44 0.002
Maximum diameter of all cerebral metastases    
 ≤18 mm (n = 75) 82 63  
 ≥19 mm (n = 73) 72 59 0.16
Main site of cerebral metastases    
 Supratentorial (n = 127) 77 59  
 Infratentorial (n = 21) 82 72 0.39
Extra-cerebral metastases    
 No (n = 95) 81 63  
 Yes (n = 53) 73 57 0.36
Interval from lung cancer diagnosis to irradiation    
 ≤11 months (n = 77) 83 58  
 ≥12 months (n = 71) 73 62 0.75
  1. Significant p-values are given in bold.