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Table 2 Local control of the treated cerebral metastases (univariate analysis)

From: Radiosurgery alone versus radiosurgery plus whole-brain irradiation for very few cerebral metastases from lung cancer

  At 6 months At 12 months P-value
Treatment approach    
 Radiosurgery alone (n = 98) 90 80  
 Radiosurgery + WBI (n = 50) 98 86 0.61
Radiosurgery dose    
 <20 Gy (n = 63) 88 76  
 ≥20 Gy (n = 85) 97 87 0.39
Age    
 ≤59 years (n = 76) 93 89  
 ≥60 years (n = 72) 93 73 0.50
Gender    
 Female (n = 68) 95 84  
 Male (n = 80) 90 80 0.70
ECOG Performance Score    
 0-1 (n = 93) 96 88  
 2 (n = 55) 86 70 < 0.001
Histology    
 Adenocarcinoma (n = 92) 95 86  
 Others (n = 56) 89 76 0.16
Number of cerebral metastases    
 1 (n = 90) 93 81  
 2-3 (n = 58) 92 84 0.39
Maximum diameter of all cerebral metastases    
 ≤18 mm (n = 75) 91 87  
 ≥19 mm (n = 73) 95 74 0.051
Main site of cerebral metastases    
 Supratentorial (n = 127) 93 81  
 Infratentorial (n = 21) 88 88 0.20
Extra-cerebral metastases    
 No (n = 95) 94 84  
 Yes (n = 53) 90 79 0.10
Interval from lung cancer diagnosis to irradiation    
 ≤11 months (n = 77) 97 83  
 ≥12 months (n = 71) 89 80 0.46
  1. Significant p-values are given in bold.