Table 2 Relationship between the expression of netrin-1 and clinicopathologic factors in BC patients
From: PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer
Factors | Group | Netrin-1 expression | X2 | P value | |
|---|---|---|---|---|---|
High(%) | Low(%) | ||||
Gender | Male | 49(40.9%) | 28(23.3%) | 0.037 | 0.213 |
female | 28(23.3%) | 15(12.5%) | |||
Age at surgery | <55 | 24(20.0%) | 23(19.2%) | 1.984 | 0.198 |
≥55 | 25(20.8%) | 48(40.0%) | |||
Histologic grade | G1 | 3(2.5%) | 20(16.7%) | 7.632 | 0.024 |
G2 | 38(31.6%) | 26(21.7%) | |||
G3 | 29(24.2%) | 4(3.3%) | |||
PT Stage | T1 | 7(5.8%) | 28(23.3%) | 21.135 | 0.031 |
T2 | 11(9.2%) | 24(20.0%) | |||
T3 | 16(13.4%) | 9(7.5%) | |||
T4 | 21(17.5%) | 4(3.3%) | |||
Tumor size(mm) | <10 | 5(4.2%) | 16(13.3%) | 1.794 | 0.153 |
10-30 | 32(26.7%) | 24(20.0%) | |||
>30 | 24(20.0%) | 19(15.8%) | |||
Multiplicity | Unifocal | 26(21.7%) | 26(21.7%) | 1.782 | 0.264 |
Multifocal | 32(26.6%) | 36(30.0%) | |||
Recurrence | Yes | 52(43.3%) | 30(25.0%) | 32.236 | 0.658 |
No | 24(20.0%) | 14(11.7%) | |||
Metastasis | Yes | 21(17.5%) | 5(4.2%) | 10.896 | 0.002 |
No | 9(7.5%) | 85(70.8%) | |||