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Table 2 Relationship between the expression of netrin-1 and clinicopathologic factors in BC patients

From: PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer

Factors Group Netrin-1 expression X2 P value
High(%) Low(%)
Gender Male 49(40.9%) 28(23.3%) 0.037 0.213
female 28(23.3%) 15(12.5%)
Age at surgery <55 24(20.0%) 23(19.2%) 1.984 0.198
≥55 25(20.8%) 48(40.0%)
Histologic grade G1 3(2.5%) 20(16.7%) 7.632 0.024
G2 38(31.6%) 26(21.7%)
G3 29(24.2%) 4(3.3%)
PT Stage T1 7(5.8%) 28(23.3%) 21.135 0.031
T2 11(9.2%) 24(20.0%)
T3 16(13.4%) 9(7.5%)
T4 21(17.5%) 4(3.3%)
Tumor size(mm) <10 5(4.2%) 16(13.3%) 1.794 0.153
10-30 32(26.7%) 24(20.0%)
>30 24(20.0%) 19(15.8%)
Multiplicity Unifocal 26(21.7%) 26(21.7%) 1.782 0.264
Multifocal 32(26.6%) 36(30.0%)
Recurrence Yes 52(43.3%) 30(25.0%) 32.236 0.658
No 24(20.0%) 14(11.7%)
Metastasis Yes 21(17.5%) 5(4.2%) 10.896 0.002
No 9(7.5%) 85(70.8%)