Magnetic resonance imaging (MRI) 14 days after GBM95 cell transplantation into one representative mouse brain. (A–D) T2 superior-inferior sequence of the mouse brain shows a shift in brain midline and collapse of lateral ventricles. (I–L) T1 superior-inferior sequence after contrast administration, enhanced contrast reflecting blood–brain barrier disruption in comparison to T1 sequence before contrast administration (E–H). Scheme depicts the injection site of GBM95 cells in mouse brain. Data are representative of four separate experiments.