Skip to main content
Figure 6 | BMC Cancer

Figure 6

From: Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation

Figure 6

PLC, PKC and MAPK inhibitors block the NA-induced PC3 cell survival. Cell growth was assessed by MTT assay in PC3 cells treated for 24 h with vehicle (control) or NA (100 μM), alone or in combination with chelerythrine (0.5 μM), U73122 (5 μM) and PD98059 (50 μM). Data shown are the mean ± SD of three separate experiments. Statistical analysis was performed by comparing NA-treated with control cells (*), NA + chelerythrine-, NA + PD98059-, NA + U73122- and NA + chelerythrine + PD98059 + U73122- with NA-treated cells (#) and NA + chelerythrine + PD98059 + U73122- with NA + chelerythrine-, NA + PD98059- and NA + U73122-treated cells (§), p ≤ 0.01.

Back to article page