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Table 4 Total list of most down-regulated genes following h HSS1 overexpression in A172 cells

From: Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis

Symbol

Gene name

FC

MCM6

Minichromosome Maintenance Complex Component 6

-1.501

C6orf52

Chromosome 6 Open Reading Frame 52

-1.501

FERMT3

Fermitin Family Member 3

-1.533

SMC2

Structural Maintenance of Chromosomes 2

-1.546

SRPX

Sushi-repeat Containing Protein, X-linked

-1.549

SHCBP1

Shc Sh2-domain Binding Protein 1

-1.564

GPSM2

G-protein Signaling Modulator 2

-1.564

NES

Nestin

-1.565

SYCP2

Synaptonemal Complex Protein 2

-1.575

MCM10

Minichromosome Maintenance Complex Component 10

-1.576

EZH2

Enhancer of Zeste Homolog 2 (Drosophila)

-1.58

TMTC2

Transmembrane and Tetratricopeptide Repeat Containing 2

-1.594

FAM129A

Family with Sequence Similarity 129, Member A

-1.596

TMEFF2

Transmembrane Protein with Egf-like and Two Follistatin-like Domains 2

-1.604

CTSL2

Cathepsin L2

-1.613

ETV1

Ets Variant 1

-1.614

SGOL2

Shugoshin-like 2 (S. Pombe)

-1.62

ERCC6L

Excision Repair Cross-complementing Rodent Repair Deficiency, Complementation Group 6-like

-1.621

KRT15

Keratin 15

-1.641

SDPR

Serum Deprivation Response

-1.656

ACAT2

Acetyl-coa Acetyltransferase 2

-1.7

BDKRB1

Bradykinin Receptor B1

-1.709

CFI

Complement Factor I

-1.711

GPD2

Glycerol-3-phosphate Dehydrogenase 2 (Mitochondrial)

-1.722

TMOD1

Tropomodulin 1

-1.729

FAM64A

Family with Sequence Similarity 64, Member A

-1.755

ANO5

Anoctamin 5

-1.782

LRRC15

Leucine Rich Repeat Containing 15

-1.812

PAGE1

P Antigen Family, Member 1 (Prostate Associated)

-1.822

XRCC2

X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 2

-1.863

EMP2

Epithelial Membrane Protein 2

-1.868

CD180

Cd180 Molecule

-1.926

ELOVL6

Elovl Fatty Acid Elongase 6

-1.931

PLCXD3

Phosphatidylinositol-specific Phospholipase C, X Domain Containing 3

-1.938

C7orf69

Chromosome 7 Open Reading Frame 69

-1.941

DMD

Dystrophin

-1.947

MNS1

Meiosis-specific Nuclear Structural 1

-1.949

FAM115C

Family with Sequence Similarity 115, Member C

-2.005

TEK

Tek Tyrosine Kinase, Endothelial

-2.099

CHRM3

Cholinergic Receptor, Muscarinic 3

-2.122

RGS16

Regulator of G-protein Signaling 16

-2.144

SULT1B1

Sulfotransferase Family, Cytosolic, 1b, Member 1

-2.478

ANKRD30B

Ankyrin Repeat Domain 30b

-2.592

B3GALT1

Udp-gal:betaglcnac Beta 1,3-galactosyltransferase, Polypeptide 1

-2.841

XIRP2

Xin Actin-binding Repeat Containing 2

-3.387

POTEB

Pote Ankyrin Domain Family, Member B (includes others)

-6.162

CCDC102B

Coiled-coil Domain Containing 102b

-11.348

  1. FC represents fold change at q ≤ 0.05 of a gene following hHSS1 modulation compared to cells stably transfected with vector control.