Skip to main content

Table 4 Total list of most down-regulated genes following h HSS1 overexpression in A172 cells

From: Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis

Symbol Gene name FC
MCM6 Minichromosome Maintenance Complex Component 6 -1.501
C6orf52 Chromosome 6 Open Reading Frame 52 -1.501
FERMT3 Fermitin Family Member 3 -1.533
SMC2 Structural Maintenance of Chromosomes 2 -1.546
SRPX Sushi-repeat Containing Protein, X-linked -1.549
SHCBP1 Shc Sh2-domain Binding Protein 1 -1.564
GPSM2 G-protein Signaling Modulator 2 -1.564
NES Nestin -1.565
SYCP2 Synaptonemal Complex Protein 2 -1.575
MCM10 Minichromosome Maintenance Complex Component 10 -1.576
EZH2 Enhancer of Zeste Homolog 2 (Drosophila) -1.58
TMTC2 Transmembrane and Tetratricopeptide Repeat Containing 2 -1.594
FAM129A Family with Sequence Similarity 129, Member A -1.596
TMEFF2 Transmembrane Protein with Egf-like and Two Follistatin-like Domains 2 -1.604
CTSL2 Cathepsin L2 -1.613
ETV1 Ets Variant 1 -1.614
SGOL2 Shugoshin-like 2 (S. Pombe) -1.62
ERCC6L Excision Repair Cross-complementing Rodent Repair Deficiency, Complementation Group 6-like -1.621
KRT15 Keratin 15 -1.641
SDPR Serum Deprivation Response -1.656
ACAT2 Acetyl-coa Acetyltransferase 2 -1.7
BDKRB1 Bradykinin Receptor B1 -1.709
CFI Complement Factor I -1.711
GPD2 Glycerol-3-phosphate Dehydrogenase 2 (Mitochondrial) -1.722
TMOD1 Tropomodulin 1 -1.729
FAM64A Family with Sequence Similarity 64, Member A -1.755
ANO5 Anoctamin 5 -1.782
LRRC15 Leucine Rich Repeat Containing 15 -1.812
PAGE1 P Antigen Family, Member 1 (Prostate Associated) -1.822
XRCC2 X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 -1.863
EMP2 Epithelial Membrane Protein 2 -1.868
CD180 Cd180 Molecule -1.926
ELOVL6 Elovl Fatty Acid Elongase 6 -1.931
PLCXD3 Phosphatidylinositol-specific Phospholipase C, X Domain Containing 3 -1.938
C7orf69 Chromosome 7 Open Reading Frame 69 -1.941
DMD Dystrophin -1.947
MNS1 Meiosis-specific Nuclear Structural 1 -1.949
FAM115C Family with Sequence Similarity 115, Member C -2.005
TEK Tek Tyrosine Kinase, Endothelial -2.099
CHRM3 Cholinergic Receptor, Muscarinic 3 -2.122
RGS16 Regulator of G-protein Signaling 16 -2.144
SULT1B1 Sulfotransferase Family, Cytosolic, 1b, Member 1 -2.478
ANKRD30B Ankyrin Repeat Domain 30b -2.592
B3GALT1 Udp-gal:betaglcnac Beta 1,3-galactosyltransferase, Polypeptide 1 -2.841
XIRP2 Xin Actin-binding Repeat Containing 2 -3.387
POTEB Pote Ankyrin Domain Family, Member B (includes others) -6.162
CCDC102B Coiled-coil Domain Containing 102b -11.348
  1. FC represents fold change at q ≤ 0.05 of a gene following hHSS1 modulation compared to cells stably transfected with vector control.