Table 2 37 most down-regulated genes following h HSS1 overexpression in U87 cells

DHCR24

24-dehydrocholesterol Reductase

-6.046

FOS

Fbj Murine Osteosarcoma Viral Oncogene Homolog

-6.103

COL1A1

Collagen, Type I, Alpha 1

-6.132

PDK3

Pyruvate Dehydrogenase Kinase, Isozyme 3

-6.236

PGF

Placental Growth Factor

-6.268

CASC5

Cancer Susceptibility Candidate 5

-6.276

KIF11

Kinesin Family Member 11

-6.342

ERCC6L

Excision Repair Cross-complementing Rodent Repair Deficiency, Complementation Group 6-like

-6.36

KIF15

Kinesin Family Member 15

-6.494

SPC25

Spc25, Ndc80 Kinetochore Complex Component, Homolog (S. Cerevisiae)

-6.902

C7orf68

Chromosome 7 Open Reading Frame 68

-7.093

IGFBP1

Insulin-like Growth Factor Binding Protein 1

-7.129

FAM70A

Family with Sequence Similarity 70, Member A

-7.265

ESCO2

Establishment of Cohesion 1 Homolog 2 (S. Cerevisiae)

-7.283

PTPRF

Protein Tyrosine Phosphatase, Receptor Type, F

-7.283

GPR155

G Protein-coupled Receptor 155

-7.323

HIST1H2BM

Histone Cluster 1, H2bm

-7.326

NID1

Nidogen 1

-7.326

MKI67

Antigen Identified by Monoclonal Antibody Ki-67

-7.88

ELMO1

Engulfment and Cell Motility 1

-7.918

DOK5

Docking Protein 5

-7.943

FAM111B

Family with Sequence Similarity 111, Member B

-7.975

RRM2

Ribonucleotide Reductase M2

-8.078

MYBL2

V-myb Myeloblastosis Viral Oncogene Homolog (Avian)-like 2

-8.361

IGFBP3

Insulin-like Growth Factor Binding Protein 3

-8.394

SLFN11

Schlafen Family Member 11

-8.461

C4orf49

Chromosome 4 Open Reading Frame 49

-8.636

FAM115C

Family with Sequence Similarity 115, Member C

-10.234

ACPP

Acid Phosphatase, Prostate

-10.234

APLN

Apelin

-10.699

GLB1L2

Galactosidase, Beta 1-like 2

-10.894

TIMP3

Timp Metallopeptidase Inhibitor 3

-10.898

MT1M

Metallothionein 1 m

-11.858

BEND5

Ben Domain Containing 5

-12.104

TXNIP

Thioredoxin Interacting Protein

-12.625

HIST1H1A

Histone Cluster 1, H1a

-15.458

THBS1

Thrombospondin 1

-18.526