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Table 2 37 most down-regulated genes following h HSS1 overexpression in U87 cells

From: Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis

Symbol Gene name FC
DHCR24 24-dehydrocholesterol Reductase -6.046
FOS Fbj Murine Osteosarcoma Viral Oncogene Homolog -6.103
COL1A1 Collagen, Type I, Alpha 1 -6.132
PDK3 Pyruvate Dehydrogenase Kinase, Isozyme 3 -6.236
PGF Placental Growth Factor -6.268
CASC5 Cancer Susceptibility Candidate 5 -6.276
KIF11 Kinesin Family Member 11 -6.342
ERCC6L Excision Repair Cross-complementing Rodent Repair Deficiency, Complementation Group 6-like -6.36
KIF15 Kinesin Family Member 15 -6.494
SPC25 Spc25, Ndc80 Kinetochore Complex Component, Homolog (S. Cerevisiae) -6.902
C7orf68 Chromosome 7 Open Reading Frame 68 -7.093
IGFBP1 Insulin-like Growth Factor Binding Protein 1 -7.129
FAM70A Family with Sequence Similarity 70, Member A -7.265
ESCO2 Establishment of Cohesion 1 Homolog 2 (S. Cerevisiae) -7.283
PTPRF Protein Tyrosine Phosphatase, Receptor Type, F -7.283
GPR155 G Protein-coupled Receptor 155 -7.323
HIST1H2BM Histone Cluster 1, H2bm -7.326
NID1 Nidogen 1 -7.326
MKI67 Antigen Identified by Monoclonal Antibody Ki-67 -7.88
ELMO1 Engulfment and Cell Motility 1 -7.918
DOK5 Docking Protein 5 -7.943
FAM111B Family with Sequence Similarity 111, Member B -7.975
RRM2 Ribonucleotide Reductase M2 -8.078
MYBL2 V-myb Myeloblastosis Viral Oncogene Homolog (Avian)-like 2 -8.361
IGFBP3 Insulin-like Growth Factor Binding Protein 3 -8.394
SLFN11 Schlafen Family Member 11 -8.461
C4orf49 Chromosome 4 Open Reading Frame 49 -8.636
FAM115C Family with Sequence Similarity 115, Member C -10.234
ACPP Acid Phosphatase, Prostate -10.234
APLN Apelin -10.699
GLB1L2 Galactosidase, Beta 1-like 2 -10.894
TIMP3 Timp Metallopeptidase Inhibitor 3 -10.898
MT1M Metallothionein 1 m -11.858
BEND5 Ben Domain Containing 5 -12.104
TXNIP Thioredoxin Interacting Protein -12.625
HIST1H1A Histone Cluster 1, H1a -15.458
THBS1 Thrombospondin 1 -18.526
  1. FC represents fold change at q ≤ 0.05 of a gene following hHSS1 modulation compared to cells stably transfected with vector control.