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Table 1 21 most up-regulated genes following h HSS1 overexpression in U87 cells

From: Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis

Symbol

Gene name

FC

IL13RA2

Interleukin 13 Receptor, Alpha 2

112.836

CT45A5

Cancer/testis Antigen Family 45, Member A5

37.258

ATP6V0D2

Atpase, H+ Transporting, Lysosomal 38 kda, V0 Subunit D2

17.409

C3AR1

Complement Component 3a Receptor 1

13.828

IL1RN

Interleukin 1 Receptor Antagonist

12.769

PNLIPRP3

Pancreatic Lipase-related Protein 3

11.422

LOC654433

Hypothetical Loc654433

11.361

LOC151760

Hypothetical Loc151760

10.637

FAM198B

Family with Sequence Similarity 198, Member B

8.365

GDF15

Growth Differentiation Factor 15

8.017

ANKRD1

Ankyrin Repeat Domain 1 (Cardiac Muscle)

7.661

FBXO32

F-box Protein 32

7.469

RSPO3

R-spondin 3 Homolog (Xenopus Laevis)

7.223

NR0B1

Nuclear Receptor Subfamily 0, Group B, Member 1

6.862

IL1A

Interleukin 1, Alpha

6.842

GCNT3

Glucosaminyl (N-acetyl) Transferase 3, Mucin Type

6.809

GABRA2

Gamma-aminobutyric Acid (Gaba) a Receptor, Alpha 2

6.791

NCAM2

Neural Cell Adhesion Molecule 2

6.704

ANO3

Anoctamin 3

6.597

ADAMTS5

Adam Metallopeptidase with Thrombospondin Type 1 Motif, 5

6.263

CD55

Cd55 Molecule, Decay Accelerating Factor for Complement (Cromer Blood Group)

6.159

  1. FC represents fold change at q ≤ 0.05 of a gene following hHSS1 modulation compared to cells stably transfected with vector control.