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Table 2 ER, PR, HER2 and Gb3 expression in HBCx

From: Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds

id IHC ESL FACS Gb3 extraction
ER PR HER2 Gb3 n count n pop % min fluo Ratio MFI % max fluo Ratio MFI ng Gb3/mg of tissue
BC11 - - - - 31499 1 100 1.5 x x N.A.
BC138 - - - + 10579 2 85 1.2 15 13.1 2.7
BC143 - - - - 9704 1 100 1.1 x x 0.0
BC147 - - - + 9051 2 85.6 2.9 14.7 22.9 45.7
BC151 - - + - 2032 1 100 1.0 x x 0.0
BC152 - - - - 8444 1 100 1.0 x x 15.0
BC162 - - - + 25850 1 100 5.8 x x N.A.
BC174 - - - + 26528 2 23.7 2.9 76.3 30.1 29.0
BC389 - - + + 27074 1 100 2.6 x x N.A.
BC52 + - - + 20355 2 67.4 3.8 32.6 29.7 200.0
BC73 - - - - 20583 1 100 1.2 x x 5.9
  1. +: positive; -: negative; n count: number of counted cells; n pop: number of present cell populations; % min fluo: percentage of cells expressing low or no Gb3 expression; % max fluo: percentage of cells with higher Gb3 expression. N.A.: data not available.