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Figure 1 | BMC Cancer

Figure 1

From: Overexpression of sphingosine-1-phosphate receptor 1 and phospho-signal transducer and activator of transcription 3 is associated with poor prognosis in rituximab-treated diffuse large B-cell lymphomas

Figure 1

S1PR1 and pSTAT3 immunostaining patterns. (A) Reactive mantle zone B-cells and endothelial cells express S1PR1. S1PR1 immunostaining was considered to be negative for cases with no staining (B) or weaker staining than mantle zone B-cells (C) and positive for cases with similar to or stronger staining than mantle zone B-cells (D). (E) Histiocytes and endothelial cells are stained for pSTAT3. pSTAT3 immunostaining was considered negative for cases with no staining (F) or cytoplasmic staining (G) and positive for the cases with nuclear staining in tumor cells (H).

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