Figure 2

ACM from viscerally obese EAC patients alters mitochondrial-associated gene expression. OE33 cells were treated with ACM from non-obese (n = 3) and obese (n = 3) EAC patients for 24 h and the expression of 84 mitochondrial-associated genes was measured by qPCR-based arrays. (A) The expression of 13 genes was upregulated ≥ 1.5-fold following treatment with ACM from obese EAC patients, when compared to ACM from non-obese patients. Data are presented as the mean ± SEM. Analysis was performed by two-tailed Student’s t-test, *p < 0.05. (B) The expression of 6 genes was downregulated ≥ 1.5-fold following treatment with ACM from obese EAC patients, when compared to ACM from non-obese patients.