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Table 1 IC50 values for anticancer drugs in SGC7901/DDP cells

From: Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance

 

Doxorubicin (μg/mL)

5-fluorouracil (μg/mL)

Cisplatin (μg/mL)

E2F1

1.52 ± 0.15*

5.22 ± 0.13*

3.52 ± 0.15*

GFP

0.53 ± 0.09

3.85 ± 1.01

2.26 ± 0.38

NC

0.61 ± 0.12

4.12 ± 0.72

2.52 ± 0.83

  1. IC50 values were evaluated by CCK-8 assay. Each experiment was conducted in triplicate. Data are expressed as means ± SD of four independent experiments. One-way analysis of variance followed by Dunnett’s multiple comparison test revealed statistical differences of *P < 0.05 for the E2F1 group versus the GFP group and NC group.