Figure 3
From: Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance
Overexpression of E2F1 decreased GAX and TAp73, and increased MDR1, MRP, ZEB1, and ZEB2 protein expression. A, B: Protein expression levels of MDR1, MRP, TAp73, GAX, ZEB1, and ZEB2 were determined by western blotting. C, D: Reciprocal immunoprecipitation assays and western blot analysis of endogenous E2F1 and MRP interaction in SGC7901/DDP cells. E: In vitro pull-down assays using 6xHis-tagged MRP (His-MRP), GST-E2F1 and GST.