BMC Cancer

Table 4 Clinico-pathological parameters in relation to ST6GAL1 promoter methylation

From: Epigenetic inactivation of ST6GAL1 in human bladder cancer

		ST6GAL1methylation^b
		n ^a	negative	positive	P-value^c	Spearmanrs
*Parameter:*
Age at diagnosis
	≤69 years	29	19	10	0.858	-0.24
	>69 years	31	21	10	0.858	-0.24
Gender
	Female	9	6	3	1.000	<0.001
	Male	51	34	17	1.000	<0.001
Tumor subtype
	Non-invasive	16	12	4	0.343	0.167
	Invasive	31	18	13	0.343	0.167
Histological tumor grade^d
	Low grade	14	11	3	0.347	0.139
	High grade	46	29	17	0.347	0.139
Tumor stage^d
	pTa-pT1	19	15	4	0.073	0.276
	pT2-pT4	27	14	13	0.073	0.276
ST6GAL1 mRNA expression^e
	Low	18	9	9	0.022	-0.355
	High	30	25	5

^aOnly patients with primary bladder cancer were included; ^bbased on MSP; ^cFisher’s exact test; ^daccording to WHO 2004 classification; ^ecut-off: 0.5 in relation to NU expression; significant p-values are marked in bold face.

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