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Table 4 Clinico-pathological parameters in relation to ST6GAL1 promoter methylation

From: Epigenetic inactivation of ST6GAL1 in human bladder cancer

  ST6GAL1methylationb  
  n a negative positive P-valuec Spearmanrs
Parameter:   
Age at diagnosis      
  ≤69 years 29 19 10 0.858 -0.24
  >69 years 31 21 10
Gender   
  Female 9 6 3 1.000 <0.001
  Male 51 34 17
Tumor subtype   
  Non-invasive 16 12 4 0.343 0.167
  Invasive 31 18 13
Histological tumor graded      
  Low grade 14 11 3 0.347 0.139
  High grade 46 29 17
Tumor staged      
  pTa-pT1 19 15 4 0.073 0.276
  pT2-pT4 27 14 13
ST6GAL1 mRNA expressione      
  Low 18 9 9 0.022 -0.355
  High 30 25 5   
  1. aOnly patients with primary bladder cancer were included; bbased on MSP; cFisher’s exact test; daccording to WHO 2004 classification; ecut-off: 0.5 in relation to NU expression; significant p-values are marked in bold face.