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Table 3 Clinico-pathological parameters of high grade, invasive bladder tumors in relation to ST6GAL1 protein expression

From: Epigenetic inactivation of ST6GAL1 in human bladder cancer

  ST6GAL1 IRSb  
  n a low(IRS 0–3) high(IRS 4–12) P-valuec Spearmanrs
Parameter:   
Age at diagnosis      
  ≤69 years 27 10 17 0.987 0.002
  >69 years 38 14 24
Gender   
  Female 21 8 13 0.894 0.017
  Male 44 16 28
Histological tumor graded      
  G2 7 4 3 0.247 0.146
  G3 58 20 38
Tumor stagee      
  pT1-pT2 29 7 22 0.056 -0.238
  pT3-pT4 36 22 19
Lymph node status      
  Negative 39 11 28 0.017 -0.321
  Positive 16 10 6   
  1. aOnly patients with primary bladder cancer were included; bcut-off: median immunoreactive score (IRS) according to Remmele and Stegner [23]; cFisher’s exact test; daccording to WHO 1973 classification according to WHO 2004 classification; eaccording to WHO 2004 classification; significant p-values are marked in bold face.