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Table 3 Clinico-pathological parameters of high grade, invasive bladder tumors in relation to ST6GAL1 protein expression

From: Epigenetic inactivation of ST6GAL1 in human bladder cancer

 

ST6GAL1 IRSb

 
 

n a

low(IRS 0–3)

high(IRS 4–12)

P-valuec

Spearmanrs

Parameter:

  

Age at diagnosis

     
 

≤69 years

27

10

17

0.987

0.002

 

>69 years

38

14

24

Gender

  
 

Female

21

8

13

0.894

0.017

 

Male

44

16

28

Histological tumor graded

     
 

G2

7

4

3

0.247

0.146

 

G3

58

20

38

Tumor stagee

     
 

pT1-pT2

29

7

22

0.056

-0.238

 

pT3-pT4

36

22

19

Lymph node status

     
 

Negative

39

11

28

0.017

-0.321

 

Positive

16

10

6

  
  1. aOnly patients with primary bladder cancer were included; bcut-off: median immunoreactive score (IRS) according to Remmele and Stegner [23]; cFisher’s exact test; daccording to WHO 1973 classification according to WHO 2004 classification; eaccording to WHO 2004 classification; significant p-values are marked in bold face.