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Table 2 Patient demographics and clinical characteristics of bone DLBCL

From: Clinical characteristics and prognostic factors of bone lymphomas: focus on the clinical significance of multifocal bone involvement by primary bone large B-cell lymphomas

Parameter

uPB-DLBCL

mPB-DLBCL

SB-DLBCL

Total

37

23

23

Age range, years

15-89

17-82

29-82

Median age, years

53.0

60.0

54.0

Mean age, years

52.9

53.4

55.0

<60, n (%)

22(59.5)

11(47.8)

15(65.2)

ā‰„60, n (%)

15(40.5)

12(52.2)

8(34.8)

Sex

Ā Ā Ā 

Male, n (%)

22(59.5)

14(60.9)

9(39.1)

Female, n (%)

15(40.5)

9(39.1)

14(60.9)

Male :female ratio

1.5:1

1.6:1

0.6:1

Race

Ā Ā Ā 

White, n (%)

33(89.2)

21(91.3)

17(73.9)

Black, n (%)

2(5.4)

1(4.3)

3(13.0)

Unknown, n (%)

2(5.4)

1(4.3)

3(13.0)

B symptoms, n (%)

7(18.9)

8(34.8)

8(34.8)

LDH

Ā Ā Ā 

Normal

23(79.3)

5(29.4)

8(57.1)

Elevated

6(20.7)

12(70.6)

6(42.9)

Lymph node involvement, n (%)

4(10.8)*

9(39.1)*

14(60.9)**

Bone marrow involvement, n (%)

3(8.1)

5(21.7)

7(30.4)

Number of bone sites, n (%)

Ā Ā Ā 

Unifocal

37(100.0)

0(0)

7(30.4)

Multifocal

0(0)

23(100.0)

16(69.6)

Sites, n (%)

Ā Ā Ā 

Appendicular

29(78.4)

10(43.5)

7(30.4)

Axial

8(21.6)

2(8.7)

9(39.1)

Both

0(0)

11(47.8)

7(30.4)

Stage, n (%)

Ā Ā Ā 

IE

30(81.1)

0(0)

1(4.3)

IIE

4(10.8)

0(0)

2(8.7)

IIIE

0(0)

0(0)

0(0)

IVE

3(8.1)

23(100.0)

20(87.0)

  1. Abbreviations uPB-DLBCL: primary bone diffuse large B-cell lymphoma with unifocal bone disease; mPB-DLBCL: primary bone diffuse large B-cell lymphoma with multifocal bone disease; SB-DLBCL: secondary bone diffuse large B-cell lymphoma.
  2. *Patients with regional lymph node enlargement.
  3. **Patients with both regional and supraregional or systemic lymph node involvements.