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Table 3 ER results among different groups of patients

From: The prevalence of estrogen receptor-negative breast cancer in Ethiopia

Parameter

ER: N (%) 352 stained tumours

  
 

Positive (% in row or mean and standard deviation)

Negative (% in row or mean and standard deviation)

ER-negative vs. ER-positive crude RR (95% CI)

ER-negative vs. ER-positive adjusted* RR (95% CI)

Total population n = 352

230 (65.3)

122 (34.7)

  

Age [years] (mean and standard deviation)

43.0 (13.7)

40.1 (12.6)

Increase 5 yrs 1.02 (0.98–1.01)

Increase 5 yrs 0.94 (0.89–1.00)

Tumour size [cm] (mean and standard deviation; n = 168 results available)

5.47 (3.3)

6.06 (3.3)

Increase 1 cm 1.03 (0.98–1.08)

Increase 1 cm 1.03 (0.97–1.08)

Place of origin

    

 Addis Ababa

123 (67.2)

60 (32.8)

Reference

Reference

 Non-Addis Ababa

89 (63.6)

51 (36.4)

1.11 (0.82–1.50)

1.03 (0.76–1.41)

 Unknown

18 (62.1)

11 (37.9)

1.16 (0.69–1.93)

1.10 (0.66–1.82)

Menopausal status

    

 Premenopausal

89 (61.4)

56 (38.6)

1.17 (0.87–1.59)

0.81 (0.54–1.23)

 Postmenopausal

104 (67.1)

51 (32.9)

Reference

Reference

 unknown

37 (71.2)

15 (28.8)

0.88 (0.54–1.42)

0.62 (0.36–1.07)

Stage (UICC)

    

 1 and 2

24 (68.6)

11 (31.4)

0.89 (0.53–1.52)

0.92 (0.54–1.56)

 3

109 (64.9)

59 (35.1)

Reference

Reference

 4

48 (67.6)

23 (32.4)

0.92 (0.62–1.37)

0.96 (0.65–1.42)

 Unknown

49 (62.8)

29 (37.2)

1.06 (0.74–1.51)

1.06 (0.75–1.51)

Histology

    

 Ductal

171 (64.5)

94 (35.5)

Reference

Reference

 Lobular

12 (60.0)

8 (40.0)

1.13 (0.64–1.98)

1.05 (0.60–1.85)

 Other/unspecified

47 (70.2)

20 (29.8)

0.84 (0.56–1.26)

0.83 (0.56–1.24)

Progesterone receptor

    

 Positive

162 (92.0)

14 (8.0)

Reference

Reference

 Negative

62 (36.9)

106 (63.1)

7.93 (4.74–13.28)

7.81 (4.66–13.09)

 Unknown

6 (75.0)

2 (25.0)

3.14 (0.86–11.55)

3.47 (0.94–12.78)

Basis of hormone receptor diagnosis

    

 Primary operation

117 (67.2)

57 (32.8)

Reference

Reference

 Recurrence

62 (58.5)

44 (41.5)

1.12 (0.96–1.31)

1.08 (0.91–1.27)

 Unknown basis

51 (70.8)

21 (29.2)

0.89 (0.59–1.35)

0.87 (0.58–1.33)

Patho-specimen for diagnosis

    

 FNAC+

92 (72.4)

35 (27.6)

0.67 (0.48–0.94)

0.71 (0.51–0.98)

 Tumour specimen

114 (59.1)

79 (40.9)

Reference

Reference

 Unknown

24 (75.0)

8 (25.0)

0.61 (0.33–1.14)

0.61 (0.33–1.16)

  1. +FNAC – fine needle aspiration cytology.
  2. *Risk ratios were adjusted for age and stage, unless this was the variable of interest, RR for age was not adjusted.