Multiple pregnancies, hepatitis C, and risk for hepatocellular carcinoma in Egyptian women

BMC Cancer

Table 2 Multivariable regression analyses of the association between hepatitis C viral infection (HCV), pregnancy number and hepatocellular carcinoma among Egyptian women

Variable	Adjusted OR (95% CI)*
Model 1
HCV infection
No	Reference
Yes	13.50 (8.09-22.53)
Model 2
Pregnancy number
≤ 5 pregnancies	Reference
> 5 pregnancies	1.84 (1.17-2.89)
Model 3
HCV infection among women with ≤ 5 pregnancies
No	Reference
Yes	6.57 (3.04-14.25)
HCV infection among women with > 5 pregnancies
No	Reference
Yes	21.42 (10.43-44.00)
Pregnancy number among women without HCV infection
≤ 5 pregnancies	Reference
> 5 pregnancies	0.72 (0.30-1.73)
Pregnancy number among women with HCV infection
≤ 5 pregnancies	Reference
> 5 pregnancies	2.33 (1.29-4.22)
Dichotomized Pregnancy number HCV interaction*
p-value	0.02

*Adjusted odds ratio (95% confidence interval); All models were adjusted for age, birthplace, education, and HBV infection.
Model 1 included HCV infection as the main variable with the adjustment covariates.
Model 2 included dichotomized pregnancy number (≤ 5 versus > 5) as the main variable with the adjustment covariates.
Model 3 included both HCV infection and dichotomized pregnancy number, and the interaction term dichotomized Pregnancy number*HCV interaction, in addition to the adjustment covariates.

ISSN: 1471-2407