Shown in the top row are the plots of the correlation between the expression fold-change along the
-axis and the corresponding average levels of methylation percentage along the
SFRP1, SFRP2, SFRP5, WIF1
in a subset of tissue samples that included normal (n = 16, HRN), hyperplastic polyps (n = 3, HP), adenomas (n = 10, Ad) and adenocarcinomas (n = 12, pT). The bottom row shows the corresponding correlations in the CRC cell line HCT116 following 5′-azadeoxycytidine treatment as well as untreated controls. The dotted lines across the plots show the fitted linear model for the data from the corresponding gene. Note that the scale of the x-axis varies between the plots depending on the range of the expression fold-change for each of the genes.