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Table 2 Clinical characteristics according to CD30-positive versus CD30-negative expression at diagnosis

From: CD30 expression is a novel prognostic indicator in extranodal natural killer/T-cell lymphoma, nasal type

Characteristics

CD30-positive

CD30-negative

P-value

No. of patients

30

66

 

Age at diagnosis (years)

  

1.000

  ≤60

26

57

 

  >60

4

9

 

Gender

  

0.668

  Male

20

41

 

  Female

10

25

 

ECOG PS

  

0.428

  0, 1

29

59

 

  ≥2

1

7

 

Subtypes

  

0.434

  UNKTL

18

45

 

  EUNKTL

12

21

 

B-symptoms

20

28

0.028

Mass (diameter) ≥5 cm

9

27

0.306

Local tumor invasion

21

40

0.375

Extranodal sites ≥2

20

37

0.327

Regional lymphadenopathy

17

34

0.639

Elevated serum LDH

18

23

0.021

Stage

  

0.684

  I, II

23

48

 

  III, IV

7

18

 

IPI score

  

0.339

  0, 1

16

42

 

  ≥2

14

24

 

KPI score

  

0.057

  0, 1

11

38

 

  ≥2

19

28

 

Treatment

  

0.627

  Chemotherapy

12

23

 

  Chemotherapy + radiotherapy

18

43

 
  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, UNKTL upper aerodigestive tract NK/T-cell lymphoma, EUNKTL extra-upper aerodigestive tract NK/T-cell lymphoma, LDH lactate dehydrogenase, IPI International Prognostic Index, KPI Korean Prognostic Index.