Table 1 Clinical characteristics of patients at diagnosis

Age at diagnosis (years) Median (range)

  ≤60

83

86.5

  >60

13

13.5

Gender

  Male

61

63.5

  Female

35

36.5

ECOG PS

  0, 1

88

91.7

  ≥2

8

8.3

Subtypes

  UNKTL

63

65.6

  EUNKTL

33

34.4

B-symptoms

48

50.0

Mass long diameter ≥5 cm

36

37.5

Local tumor invasion

61

63.5

Extranodal sites ≥2

57

59.4

Regional lymphadenopathy

51

53.1

Elevated serum LDH

41

42.7

Elevated serum β₂ M*

40

67.8

Ann Arbor stage

  I, II

71

74.0

  III, IV

25

26.0

IPI score

  0, 1

58

60.4

  ≥2

38

39.6

KPI score

  0, 1

49

51.0

  ≥2

47

49.0

CD30 expression

  Positive

30

31.2

  Negative

66

68.8

Treatment

  Chemotherapy

35

36.5

  Chemotherapy + radiotherapy

61

63.5