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Table 2 Cox proportional hazards model stratified by ypTNM stage

From: Which is the best postoperative chemotherapy regimen in patients with rectal cancer after neoadjuvant therapy?

  HR 95%CI P
Stage I    
  Chemotherapy regimens    
   5-FU 1   
   No-chemo 1.021 0.459-2.273 0.960
   Oxaliplatin 1.002 0.215-4.670 0.998
Stage II    
  ypT category    
   ypT3 1   
   ypT4a 1.187 0.291-4.841 0.811
   ypT4b 1.878 1.058-3.334 0.031
  Postoperative radiotherapy    
   No 1   
   Yes 1.870 1.159-3.018 0.010
  Histologic type    
   Adenocarcinoma 1   
   Mucinous carcinoma 1.877 1.138-3.094 0.014
   Signet-ring cell carcinoma 8.078 2.351-27.748 0.001
  Chemotherapy regimens    
   5-FU 1   
   No-chemo 1.393 0.903-2.148 0.134
   Oxaliplatin 0.926 0.438-1.956 0.840
Stage III    
  ypT category    
   ypT1 1.150 0.491-2.692 0.747
   ypT2 0.759 0.436-1.321 0.329
   ypT3 1   
   ypT4a 0.691 0.244-1.959 0.487
   ypT4b 1.592 0.934-2.713 0.088
  ypN category    
   ypN1a 1   
   ypN1b 1.233 0.825-1.844 0.306
   ypN2a 1.468 0.905-2.381 0.119
   ypN2b 2.098 1.310-3.357 0.002
  Residence location    
   Big Metro 1   
   Metro or Urban 1.147 0.822-1.600 0.419
   Less Urban or Rural 0.487 0.257-0.923 0.027
  Histologic type    
   Adenocarcinoma 1   
   Mucinous carcinoma 1.466 0.993-2.163 0.054
   Signet-ring cell carcinoma 1.220 0.459-3.239 0.690
  Histologic grade    
   Well 0.716 0.229-2.239 0.565
   Moderate 1   
   Poor 1.650 0.753-3.619 0.211
   Undifferentiated 2.817 0.891-8.910 0.078
   Unknown 1.037 0.496-2.171 0.922
  Chemotherapy regimens    
   5-FU 1   
   No-chemo 1.547 1.101-2.173 0.012
   Oxaliplatin 0.626 0.372-1.054 0.078
  1. Abbreviations: No-chemo without postoperative chemotherapy, 5-FU 5-fluorouracil, CI Confidential intervals.
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