Table 2 Cox proportional hazards model stratified by ypTNM stage

Stage I

  Chemotherapy regimens

   5-FU

1

   No-chemo

1.021

0.459-2.273

0.960

   Oxaliplatin

1.002

0.215-4.670

0.998

Stage II

  ypT category

   ypT3

1

   ypT4a

1.187

0.291-4.841

0.811

   ypT4b

1.878

1.058-3.334

0.031

  Postoperative radiotherapy

   No

1

   Yes

1.870

1.159-3.018

0.010

  Histologic type

   Adenocarcinoma

1

   Mucinous carcinoma

1.877

1.138-3.094

0.014

   Signet-ring cell carcinoma

8.078

2.351-27.748

0.001

  Chemotherapy regimens

   5-FU

1

   No-chemo

1.393

0.903-2.148

0.134

   Oxaliplatin

0.926

0.438-1.956

0.840

Stage III

  ypT category

   ypT1

1.150

0.491-2.692

0.747

   ypT2

0.759

0.436-1.321

0.329

   ypT3

1

   ypT4a

0.691

0.244-1.959

0.487

   ypT4b

1.592

0.934-2.713

0.088

  ypN category

   ypN1a

1

   ypN1b

1.233

0.825-1.844

0.306

   ypN2a

1.468

0.905-2.381

0.119

   ypN2b

2.098

1.310-3.357

0.002

  Residence location

   Big Metro

1

   Metro or Urban

1.147

0.822-1.600

0.419

   Less Urban or Rural

0.487

0.257-0.923

0.027

  Histologic type

   Adenocarcinoma

1

   Mucinous carcinoma

1.466

0.993-2.163

0.054

   Signet-ring cell carcinoma

1.220

0.459-3.239

0.690

  Histologic grade

   Well

0.716

0.229-2.239

0.565

   Moderate

1

   Poor

1.650

0.753-3.619

0.211

   Undifferentiated

2.817

0.891-8.910

0.078

   Unknown

1.037

0.496-2.171

0.922

  Chemotherapy regimens

   5-FU

1

   No-chemo

1.547

1.101-2.173

0.012

   Oxaliplatin

0.626

0.372-1.054

0.078