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Table 2 Correlation of clinicopathological characteristics and URG4 expression in cervical cancer patients

From: URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer

Characteristics   Total (n = 167) URG4 Chi-square test P-value Fisher’s exact test P-value
  Low expression High expression
  (%) (%)  
Age (y) ≥42 93 56 (60.2) 37 (39.8) 0.798 0.873
<42 74 46 (62.2) 28 (37.8)
Clinical stage Ib1 68 57 (83.8) 11 (16.2) 0.000 0.000
Ib2 59 32 (54.2) 27 (45.8)
IIa1 38 19 (50.0) 19 (50.0)
IIa2 2 0 (0.0) 2 (100.0)
T classification T1b1 113 74 (65.5) 39 (34.5) 0.005 0.003
T1b2 39 26 (66.7) 13 (33.3)
T2a 9 1 (11.1) 8 (88.9)
T2b 4 1 (25.0) 3 (75.0)
T4 2 0 (0.0) 2 (100.0)
N classification N 0 140 91 (65.0) 49 (35.0) 0.001 0.002
N 1 27 11 (40.7) 16 (59.3)
M classification Yes 7 4 (57.1) 3 (42.9) 0.827 1.000
No 160 98 (61.2) 62 (38.8)
Histological differentiation Well 8 7 (87.5) 1 (12.5) 0.058 0.069
Moderate 66 34 (51.5) 32 (48.5)
Poor 93 61 (65.6) 32 (34.0)
Expression of SCC ≤1.5 97 64 (66.0) 33 (34.0) 0.289 0.291
>1.5 51 27 (52.9) 22 (47.1)
None 19 11 (57.9) 7 (42.1)
Tumour size, cm <4 106 76 (71.7) 30 (28.3) 0.012 0.018
≥4 61 32 (52.5) 29 (47.5)
Histological type Squamous cell carcinoma 153 92 (60.1) 61 (39.9) 0.407 0.569
Adeno cell carcinoma 14 10 (71.4) 4 (28.6)
Deep stromal invasion Yes 100 55 (55.0) 45 (45.0) 0.123 0.139
No 67 47 (70.1) 20 (29.9)
Lymphovascular space involvement Yes 7 3 (42.9) 4 (57.1) 0.312 0.433
No 160 99 (61.9) 61 (38.1)
Positive parametrium Yes 5 2 (40.0) 3 (60.0) 0.326 0.378
No 162 100 (61.7) 62 (38.3)
Vaginal involvement Yes 10 1 (10.0) 9 (90.0) 0.002 0.004
No 157 101 (64.3) 56 (35.7)
Positive surgical margin Yes 3 1 (33.3) 2 (66.7) 0.320 0.561
No 164 101 (61.6) 63 (38.4)