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Figure 1 | BMC Cancer

Figure 1

From: Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1

Figure 1

Localization of nonsynonymous, somatic mutations in TNK2 and DDR1 relative to important functional domains of the proteins. All the somatic mutations were uncovered in primary endometrial tumors. Individual missense mutations (black boxes) are distinguished from frameshift mutants (black diamonds). Abbreviations: CB, clathrin binding site; CRIB, Cdc42/Rac interactive binding; DS, discoidin; SAM, sterile alpha motif; SH3, Src Homology 3; TM, transmembrane; UBA, ubiquitin associated.

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