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Table 7 VEGF mRNA expression (mean ± SE) between tumor and tumor-adjacent tissues according to VEGF 3′-UTR genotypes and haplotypes

From: Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

  Tumor-adjacent (n = 47) Tumor (n = 47) p
VEGF 1451CC (n = 32) 1.00 ± 0.45 75.37 ± 35.42 0.029
VEGF 1451CT+TT (n = 15) 1.00 ± 0.84 0.59 ± 0.30 0.125
VEGF 1612GG (n = 33) 1.00 ± 0.54 52.24 ± 35.00 0.001
VEGF 1612GA+AA (n = 14) 1.00 ± 0.63 28.36 ± 18.39 0.143
VEGF 1725GG (n = 41) 1.00 ± 0.40 30.65 ± 17.78 0.011
VEGF 1725GA+AA (n = 6) 1.00 ± 0.72 39.00 ± 27.83 0.203
VEGF 1451C/1612G/1725G (n = 61) 1.00 ± 0.35 67.56 ± 26.35 <.001
VEGF 1451T/1612G/1725G (n = 18) 1.00 ± 0.81 0.50 ± 0.25 0.133
VEGF 1451C/1612A/1725G (n = 9) 1.00 ± 0.56 10.93 ± 10.43 0.481
VEGF 1451C/1612A/1725A (n = 5) 1.00 ± 0.77 39.15 ± 27.98 0.210
  1. Standard error (SE), Vascular endothelial growth factor (VEGF). p values were calculated by Wilcoxon signed rank test.