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Table 6 VEGF mRNA expression levels (mean ± SE) according to VEGF 3′-UTR genotypes and haplotypes

From: Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

  Tumor-adjacent (n = 47) p Tumor (n = 47) p
VEGF 1451CC (n = 32) 1.00 ± 0.45 0.445 1.00 ± 0.47 0.158
VEGF 1451CT+TT (n = 15) 2.54 ± 2.13   0.02 ± 0.01  
VEGF 1612GG (n = 33) 1.00 ± 0.54 0.008 1.00 ± 0.67 0.156
VEGF 1612GA+AA (n = 14) 6.76 ± 4.24   3.67 ± 2.38  
VEGF 1725GG (n = 41) 1.00 ± 0.40 0.038 1.00 ± 0.58 0.011
VEGF 1725GA+AA (n = 6) 5.98 ± 4.30   7.61 ± 5.43  
VEGF 1451C/1612G/1725G (n = 61) 1.00 ± 0.35 0.064 1.00 ± 0.39 0.027
VEGF 1451T/1612G/1725G (n = 18) 2.61 ± 2.19   0.02 ± 0.01  
VEGF 1451C/1612A/1725G (n = 9) 2.72 ± 1.52   0.44 ± 0.42  
VEGF 1451C/1612A/1725A (n = 5) 7.92 ± 6.08   4.59 ± 3.28  
  1. Standard error (SE), Vascular endothelial growth factor (VEGF). p values were calculated by Mann–Whitney and Kruskal-Wallis tests.