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Table 6 VEGF mRNA expression levels (mean ± SE) according to VEGF 3′-UTR genotypes and haplotypes

From: Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

 

Tumor-adjacent (n = 47)

p

Tumor (n = 47)

p

VEGF 1451CC (n = 32)

1.00 ± 0.45

0.445

1.00 ± 0.47

0.158

VEGF 1451CT+TT (n = 15)

2.54 ± 2.13

 

0.02 ± 0.01

 

VEGF 1612GG (n = 33)

1.00 ± 0.54

0.008

1.00 ± 0.67

0.156

VEGF 1612GA+AA (n = 14)

6.76 ± 4.24

 

3.67 ± 2.38

 

VEGF 1725GG (n = 41)

1.00 ± 0.40

0.038

1.00 ± 0.58

0.011

VEGF 1725GA+AA (n = 6)

5.98 ± 4.30

 

7.61 ± 5.43

 

VEGF 1451C/1612G/1725G (n = 61)

1.00 ± 0.35

0.064

1.00 ± 0.39

0.027

VEGF 1451T/1612G/1725G (n = 18)

2.61 ± 2.19

 

0.02 ± 0.01

 

VEGF 1451C/1612A/1725G (n = 9)

2.72 ± 1.52

 

0.44 ± 0.42

 

VEGF 1451C/1612A/1725A (n = 5)

7.92 ± 6.08

 

4.59 ± 3.28

 
  1. Standard error (SE), Vascular endothelial growth factor (VEGF). p values were calculated by Mann–Whitney and Kruskal-Wallis tests.