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Table 1 Patients and tumor characteristics

From: Radiotherapy treatment of adrenal gland metastases from hepatocellular carcinoma: clinical features and prognostic factors

Independent variable

Patients

Kaplan-Meier survival

Univariate analysis

Multivariate analysis

n

Median (months)

P

P

Age (yr)

  

.114

n.s.

 ≤50

23

12.63 ± 4.26

  

 >50

32

13.63 ± 4.88

  

Gender

  

.411

n.s.

 Male

52

13.63 ± 1.48

  

 Female

3

7.27 ± 0.63

  

γ-GT

6 missing

 

.008

n.s

 <150

33

17.80 ± 6.51

  

 ≥150

16

5.57 ± 3.53

  

AFP level (μg/ml)

  

.027

n.s

 <400

33

15.90 ± 2.62

  

 ≥400

22

5.57 ± 2.01

  

Child-Pugh classification

  

.043

n.s

 A

45

15.27 ± 1.63

  

 B

10

5.53 ± 2.43

  

Maximal diameter of intrahepatic tumors (mm)

  

.074

n.s

 ≤80

33

15.13 ± 3.32

  

 >80

22

8.87 ± 1.46

  

Number of intrahepatic tumor(s)

  

.000

.042

 Solitary

45

15.90 ± 2.61

  

 Multiple (>2)

10

5.57 ± 3.30

  

Interval

  

.422

n.s.

 Synchronous

8

8.87 ± 1.22

  

 Metachronous

47

13.63 ± 1.52

  

Resection including liver transplantation for intrahepatic tumors

  

.483

n.s.

 Yes

35(4)

15.90 ± 2.38

  

 No

20

10.53 ± 3.17

  

Additional organ metastasis

  

.001

.00

 Yes

9

4.47 ± 0.45

  

 No

46

15.27 ± 1.63

  

Metastatic adrenal tumor size (mm)

  

.476

n.s.

 <50

21

15.13 ± 4.40

  

 ≥50

34

13.20 ± 2.02

  

Location of adrenal lesion

  

.614

n.s.

 Single adrenal

47

13.63 ± 1.42

  

 Both

8

9.27 ± 5.33

  

Radiation dose (Gy)

  

.102

.059

 ≥54

18

21.27 ± 8.46

  

 <54

37

12.93 ± 2.15

  

Primary HCC

  

.00

.003

 Controlled

38

17.80 ± 4.77

  

 Uncontrolled

17

9.77 ± 2.94

  

Response to RT

5 missing

 

.017

n.s

 PR

32

17.80 ± 8.28

  

 SD

18

12.63 ± 2.79