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Table 2 Quantitative analyses of PET findings using three tracers in patients with HNSCC

From: Hypoxia, blood flow and metabolism in squamous-cell carcinoma of the head and neck: correlations between multiple immunohistochemical parameters and PET

  [18F]FDG [18F]FETNIM [15O]H2O
Patient no. SUVa Tumor volumeb(cm3) FHVc(%) T/P ratiod Blood flow (ml/100 mg/min)
1 18.5 8.3 9.5 0.91 35.3
2 14.9 3.4 10.5 0.72 29.7
3 19.0 34.1 61.6 1.41 44.4
4 8.4 9.9 61.4 1.98 63.1
5 17.3 401.6 39.2 1.49 44.8
6 11.7 53.6 54.2 1.24 23.7
7 7.6 1.7 17.8 0.95 12.4
8 18.3 141.1 55.7 1.34 29.6
9 13.0 22.2 48.0 1.07 n.d.
10 7.8 5.5 50.5 1.11 26.2
11 28.8 23.6 19.7 1.00 19.7
12 9.6 12.6 34.0 1.02 37.9
13 7.2 5.0 10.1 0.82 24.3
14 19.6 52.6 63.2 1.37 41.0
15 5.3 1.4 62.3 1.10 31.0
Mean ± SD 13.8 ± 6.5 51.8 ± 103.2 39.8 ± 21.1 1.17 ± 0.32 33.1 ± 12.7
Median (range) 13.0 (5.3 – 28.8) 12.6 (1.4 – 401.6) 48.0 (9.5 – 63.2) 1.10 (0.72 – 1.98) 30.4 (12.4 – 63.1)
  1. astandardized uptake value.
  2. bmetabolically active volume as determined from [18F]FDG PET.
  3. cfractional hypoxic volume.
  4. dmaximum tumor-to-plasma radioactivity at 90 – 120 min.
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