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Table 1 General characteristics of the study subjects

From: Biomarkers of thyroid function and autoimmunity for predicting high-risk groups of thyroid cancer: a nested case–control study

 

Controls (n = 257)

Cases (n = 257)

P-value

Age (years), means

49.4 ± 8.9

49.4 ± 8.9

0.994

BMI (kg/m2)

   

  <23

125(48.6)

95(37.0)

0.019

  23 - <25

68(26.5)

75(29.2)

 

  ≥ 25

64(24.9)

87(33.9)

 

Family history of cancer (yes)a

93(41.0)

108(46.4)

0.245

Family history of thyroid cancer (yes)a

5(2.2)

6(2.6)

0.794

Educational level

   

  Elementary school or less

21(8.8)

23(9.8)

0.774

  Middle school

19(7.9)

16(6.8)

 

  High school

95(39.6)

84(35.9)

 

  College or more

105(43.8)

115(47.4)

 

Monthly household incomeb

   

  <200

35(16.6)

24(11.8)

0.102

  200 - <400

56(26.5)

72(35.3)

 

  >400

120(56.9)

108(52.9)

 

Marital status

   

  Married

218(90.8)

215(90.0)

0.480

  Unmarried

8(3.3)

5(2.1)

 

  Divorced/Widowed

14(5.8)

19(8.0)

 

Smoking status

   

  Nonsmoker

147(64.8)

158(69.3)

0.215

  Former smoker

33(14.5)

37(16.3)

 

  Current smoker

47(20.7)

33(14.5)

 

Alcohol consumption

   

  Nondrinker

87(36.4)

100(41.5)

0.208

  Former drinker

7(2.9)

12(5.0)

 

  Current drinker

145(60.7)

129(53.5)

 

Age at menarche (years)c

   

  ≤13

35(22.0)

31(20.5)

0.680

  14

34(21.4)

34(22.5)

 

  15

37(23.3)

28(18.5)

 

  ≥16

53(33.3)

58(38.4)

 

Menopause (yes)c

83(47.7)

79(43.9)

0.472

Age at menopause (years)c

   

  <46

16(21.1)

12(17.7)

0.185

  46 - <49

14(18.4)

8(11.8)

 

  49 - <52

14(18.4)

23(33.8)

 

  ≥52

32(42.1)

25(36.8)

 

Type of menopausec

   

  Natural

57(71.3)

51(64.6)

0.366

  Surgery, Other

23(28.8)

28(35.4)

 

Postmenopausal hormone use (ever)c

28(36.8)

20(30.8)

0.448

Parity (yes)c

157(96.3)

159(98.2)

0.315

  1. aFirst-degree relative.
  2. bUnit is 10,000 Korean won.
  3. cOnly in women.