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Figure 4 | BMC Cancer

Figure 4

From: Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer

Figure 4

Subgroup specific response to anti-cancer compounds. A) Cell line subgroup assignment based on PAM classifier. B) Expression of RAD50 and BARD1 in the 6 subgroups subgroups. C) Relative growth analysis of subgroup 1 and non-subgroup #1 cell with or without 200nM etoposide. D) Relative growth at 72 hours for subgroup #1 and other cell lines reveals marked etoposide selectivity for subgroup #1 cell lines. E) Cell line sensitivity to etoposide from the Heiser et al. published dataset (*p = 0.02, t-test).

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