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Figure 2 | BMC Cancer

Figure 2

From: Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia

Figure 2

Expression levels of STATIP1 , STAT3 , CCND1 and BCL-XL genes in response to IM/LLL-3 treatments. (A) Relative mRNA levels of STATIP1, STAT3, CCND1 and BCL-XL after 24 h of 1 μM IM treatment. (B) Relative mRNA levels of STATIP1, STAT3, CCND1 and BCL-XL after 24 h of 40 μM LLL-3 treatment. (C) Western blot analysis of STAT3 and STATIP1 protein levels and STAT3-Y705 phosphorylation 24 h after 1 μM IM treatment. (D) The protein levels were determined by densitometry analysis in ImageJ software version 1.44. All comparisons were made to untreated cells – ctrl. Ctrl: control. The data represent the mean ± SD of at least three independent experiments (*p <0.05 and **p <0.01).

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BMC Cancer

ISSN: 1471-2407

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