Table 3 miR-449b expression in relation to the clinical variables in the validation cohort
Clinical variable | Chi2–test | miR-449b expression | No miR-449b expression |
|---|---|---|---|
P-value | |||
Total number of cancer samples | 78 | 85 | |
Gleason grade | 0.27 | ||
Low (5–6) | 27 | 33 | |
Intermediate (7) | 45 | 40 | |
High (8–10) | 6 | 12 | |
Pathological stage | 0.73 | ||
T2a-c | 47 | 49 | |
T3a-b | 31 | 36 | |
Pre-operative PSA | 0.02 | ||
0-10 ng/ml | 22 | 27 | |
10-20 ng/ml | 44 | 31 | |
20- ng/ml | 12 | 27 | |
Recurrence | 0.05 | ||
Yes | 26 | 41 | |
No | 52 | 44 | |
Margin status | 0.21 | ||
Negative | 54 | 64 | |
Positive | 24 | 19 |