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Table 3 Associations between MUC1 or VEGF mRNA positivity and clinicopathologic factors

From: Expressions of MUC1 and vascular endothelial growth factor mRNA in blood are biomarkers for predicting efficacy of gefitinib treatment in non-small cell lung cancer

  MUC1 mRNA VEGF mRNA
B0 B4w B0 B4w
Positivity (n = 50) Negativity (n = 16) Positivity (n = 30 Negativity (n = 36) Positivity (n = 47) Negativity (n = 19) Positivity (n = 29) Negativity (n = 37)
Sex         
 Male 27 10 16 21 25 12 17 20
 Female 23 6 14 15 22 7 12 17
P value 0.579   0.804   0.586   0.805  
Smoking history         
 Never 15 7 7 15 13 9 7 15
 Non-never 35 9 23 21 34 10 22 22
P value 0.225   0.121   0.156   0.168  
Histology         
 ADC 26 13 13 26 24 15 12 27
 Non-ADC 24 3 17 10 23 4 17 10
P value 0.045   0.024   0.053   0.013  
Performance status         
 0-1 40 12 22 30 36 16 22 30
 2-3 10 4 8 6 11 3 7 7
P value 0.730   0.375   0.741   0.763  
Disease stage         
 IIIB 7 3 6 4 5 5 6 4
 IV 43 13 24 32 42 14 23 33
P value 0.695   0.814   0.248   0.437  
EGFR status         
 Wild-type 32 6 21 17 31 7 21 17
 Mutation 13 9 6 16 12 10 7 15
 Unknown 5 1 3 3 4 2 1 5
P value 0.083   0.102   0.058   0.095  
Tumor response         
 PR 14 11 7 18 13 12 8 17
 SD 17 3 7 13 16 4 6 14
 PD 19 2 16 5 18 3 15 6
P value 0.013   0.002   0.025   0.018  
  1. ADC, adenocarcinoma; PR, partial response; SD, stable disease; PD, progression disease.
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